ID M3Y071_MUSPF Unreviewed; 381 AA.
AC M3Y071;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000004722.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000004722.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/MEIS homeobox family.
CC {ECO:0000256|ARBA:ARBA00009661}.
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DR EMBL; AEYP01068315; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3Y071; -.
DR STRING; 9669.ENSMPUP00000004722; -.
DR Ensembl; ENSMPUT00000004804.1; ENSMPUP00000004722.1; ENSMPUG00000004760.1.
DR eggNOG; KOG0773; Eukaryota.
DR GeneTree; ENSGT00940000161057; -.
DR HOGENOM; CLU_023139_1_1_1; -.
DR InParanoid; M3Y071; -.
DR OMA; EDFPASC; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR032453; PKNOX/Meis_N.
DR PANTHER; PTHR11850:SF190; HOMEOBOX PROTEIN MEIS3-RELATED; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF16493; Meis_PKNOX_N; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 263..326
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 265..327
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 22..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 196..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..47
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 381 AA; 41986 MW; D5150D792FF8146B CRC64;
ASPQYDELPH YPGLVDSTAA LAGFPEAVPS APRAPGPYGP HRPPQPQPLG LDSDGLRREK
DEIYGHPLFP LLALVFEKCE LATCSPRDGA STGLGTPPGG DVCSSDSFNE DIAAFAKQVR
SERPLFSSNP ELDNLMIQAI QVLRFHLLEL EKVHDLCDNF CHRYITCLKG KMPIDLVIED
RDGGCREDLE DYPASCPSLP DQNNMWIRDH EDSGSVHLGT PGPSSGGLAS QSGDNSSDQG
DGLDTSVASP SSGGEDEELD QERRRNKKRG IFPKVATNIM RAWLFQHLSH PYPSEEQKKQ
LAQDTGLTIL QVNNWFINAR RRIVQPMIDQ SNRTGQSAAF SPEGQPMGGY TEAQPHMTVR
PPVYLWSMGM SLNLEGEWHY L
//
