ID M3Y0B6_MUSPF Unreviewed; 216 AA.
AC M3Y0B6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=DNA replication complex GINS protein PSF3 {ECO:0000256|RuleBase:RU367161};
GN Name=GINS3 {ECO:0000313|Ensembl:ENSMPUP00000004767.1,
GN ECO:0000313|RefSeq:XP_004744337.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000004767.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000004767.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004744337.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004744337.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000256|RuleBase:RU367161}.
CC -!- SUBUNIT: Component of the GINS complex.
CC {ECO:0000256|RuleBase:RU367161}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU367161}.
CC -!- SIMILARITY: Belongs to the GINS3/PSF3 family.
CC {ECO:0000256|ARBA:ARBA00006343, ECO:0000256|RuleBase:RU367161}.
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DR EMBL; AEYP01015549; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004744337.1; XM_004744280.3.
DR STRING; 9669.ENSMPUP00000004767; -.
DR Ensembl; ENSMPUT00000004850.1; ENSMPUP00000004767.1; ENSMPUG00000004806.1.
DR GeneID; 101672380; -.
DR KEGG; mpuf:101672380; -.
DR CTD; 64785; -.
DR eggNOG; KOG1106; Eukaryota.
DR GeneTree; ENSGT00390000001622; -.
DR HOGENOM; CLU_081646_2_0_1; -.
DR OMA; IYKEGWR; -.
DR OrthoDB; 3670282at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0071162; C:CMG complex; IEA:Ensembl.
DR GO; GO:0000811; C:GINS complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:Ensembl.
DR CDD; cd11713; GINS_A_psf3; 1.
DR CDD; cd21693; GINS_B_Psf3; 1.
DR Gene3D; 1.20.58.2050; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR010492; GINS_Psf3.
DR InterPro; IPR038437; GINS_Psf3_sf.
DR PANTHER; PTHR22768:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF3; 1.
DR PANTHER; PTHR22768; UNCHARACTERIZED; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU367161};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367161};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715}.
FT DOMAIN 67..173
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
SQ SEQUENCE 216 AA; 24489 MW; F1C6F0381C5FFC57 CRC64;
MSEAYFRVES GALGPEENFL SLDDILMSHE KLPVRTETPM PRLGAFFLER SGGPETDHAI
PQGSKLELPL WLAKGLFDNK RRIISVELPK IYQQGWRTVF SADANVVDLH KLGPHFYGFG
SQLLHFDSPE NADISQSLLQ TFIGRFRRIM DSSQNAYNED TSALVARLDE MERGLFQTGQ
KGLNDFQCWE KGQASQITAS SLVQNYKKRK LTDMDN
//
