ID M3Y5L5_MUSPF Unreviewed; 444 AA.
AC M3Y5L5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Z-DNA binding protein 1 {ECO:0000313|Ensembl:ENSMPUP00000006616.1};
DE SubName: Full=Z-DNA-binding protein 1 isoform X4 {ECO:0000313|RefSeq:XP_004759970.1};
GN Name=ZBP1 {ECO:0000313|RefSeq:XP_004759970.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000006616.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000006616.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004759970.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004759970.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AEYP01050366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004759970.1; XM_004759913.3.
DR STRING; 9669.ENSMPUP00000006616; -.
DR Ensembl; ENSMPUT00000006729.1; ENSMPUP00000006616.1; ENSMPUG00000006670.1.
DR GeneID; 101687826; -.
DR CTD; 81030; -.
DR eggNOG; ENOG502SRWE; Eukaryota.
DR GeneTree; ENSGT00390000002234; -.
DR HOGENOM; CLU_053260_0_0_1; -.
DR OMA; PATWCLA; -.
DR OrthoDB; 5266205at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003726; F:double-stranded RNA adenosine deaminase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR042371; Z_dom.
DR InterPro; IPR042361; ZBP1.
DR PANTHER; PTHR14966; Z-DNA-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR14966:SF0; Z-DNA-BINDING PROTEIN 1; 1.
DR Pfam; PF02295; z-alpha; 1.
DR SMART; SM00550; Zalpha; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50139; Z_BINDING; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 7..69
FT /note="Z-binding"
FT /evidence="ECO:0000259|PROSITE:PS50139"
FT DOMAIN 101..164
FT /note="Z-binding"
FT /evidence="ECO:0000259|PROSITE:PS50139"
FT REGION 57..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 47993 MW; 2CE2830580488919 CRC64;
MAQAPGDPDE TDLEQRILQV LRDVGSPMKS SQLAKECQVP KKNVNQVLYQ MLKESKVSQE
RPAMWGLGQG GTREVEPAEP ARPSQAELPQ QDVAAAPEEP GRQLTKQQEE IYRILKTHGP
CKALTISQKL GKKTAKQVNP DLYAMRGKHL LDLDEKSSTW AVYRPDLGGR NPAPAIIYQK
NPINMICQNG PNNHISIENS ESIQIGHGNV IVRPTASGEN GSMAPLHLPP VAPADPSSQT
SPAAAWGPQD ICLEKSVLRR VQMGHGNNMN LKSAPAKDPT ARSPSISPPV CAPTDGPEAL
FEIRMPKPGP SAEEEVAQRV RIRSCFLEDT AIGNSNRMTV SSETAGPEGA VRPEDIKRDP
GEPGKDAGAE PRSQFPHHRD QAPPGNSDVL TFISDLEAVT LESGDPHTIE DSSQVDRTPD
MDSRGQVETG TNSQALSGRA GRHQ
//
