ID   M3Y795_MUSPF            Unreviewed;       858 AA.
AC   M3Y795;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   SubName: Full=FYN binding protein 2 {ECO:0000313|Ensembl:ENSMPUP00000007202.1};
GN   Name=FYB2 {ECO:0000313|Ensembl:ENSMPUP00000007202.1};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000007202.1};
RN   [1] {ECO:0000313|Ensembl:ENSMPUP00000007202.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AEYP01029364; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01029365; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01029366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01029367; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01029368; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01029369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M3Y795; -.
DR   STRING; 9669.ENSMPUP00000007202; -.
DR   Ensembl; ENSMPUT00000007321.1; ENSMPUP00000007202.1; ENSMPUG00000007259.1.
DR   eggNOG; ENOG502RXZD; Eukaryota.
DR   GeneTree; ENSGT00530000063460; -.
DR   HOGENOM; CLU_023222_0_0_1; -.
DR   InParanoid; M3Y795; -.
DR   OMA; KPWKNFP; -.
DR   GO; GO:0001772; C:immunological synapse; IEA:Ensembl.
DR   GO; GO:0045121; C:membrane raft; IEA:Ensembl.
DR   GO; GO:0033627; P:cell adhesion mediated by integrin; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR043443; FYB1/2-like.
DR   InterPro; IPR029294; hSH3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR16830:SF1; FYN-BINDING PROTEIN 2; 1.
DR   PANTHER; PTHR16830; SH2 CONTAINING ADAPTOR PRAM-1 RELATED; 1.
DR   Pfam; PF14603; hSH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          794..854
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          163..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          355..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          445..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          606..650
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        170..211
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..374
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        445..484
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   858 AA;  96325 MW;  3973B3C8B33918F7 CRC64;
     MECGRCPASA GKAPVPREGG AAPQVGQVGH LSSGVSRALG GDCSLASANK PKRTLGPRIQ
     LWETAFVSQT LPRRKAMEGA IASPADSTYR EGLRNFKELR AKFQKFDMPL PPGPIKFSAG
     VSQKGNIGNT QSTRILANGK SLSSSHSLLP LCSSAESQLL KDQETKLAQR SEIQKCSNSP
     GPLERSSGPA VNSQKSSPLL DRNPSNAEIT NKRRVTMNES FKDKLWNWEK FSSQKSESSS
     ASLLARCACR ICHAEEQKSR GLLPKEPRIM LEIKGTQTLP SQRHLVAQRE SLTFPEDPTF
     LLFQHGKKNL ENPLPEKSPV RGSCQLVYES ELSSQAPDSE KQSVDKHQQL LKTKPLPSIE
     SLGPPPPKPP KPPVVNLQAF QKQAATISKT HTEAAVEEGC LPPESAEFEE PHNYEATISY
     LKHSGNSINL CTAKEIADST YEVEIEEPQK PRKNGLHQEL SPKYEDEDED KKEKEKEPCE
     LEPQKPQKDL PSSHLFKYSL IRSALEVFLH PVSQPRERTS PPPFLSQRTT QLQTALATWY
     LKGATRGGML GRKQVMKVLG GRRSMLPRKQ GPVSDATQTK ACLQDPKLAR HSLGHCGYVE
     TLEDTTEMPD GGACKPHSNS EETYDDVEYP GRAGPQSDLS NSFASDNEEN NEEMYEEVYK
     TKSNYPKIDL DGKEALKRLR KFFKKEKDRF KMKKNKLKEN VSAFSISLPD LELRSQEAII
     YDNVDISEKE SRDENKLKTW KPKFLMAKEK KERKGAEESE RNFFRTKKQN LEKMRMEKEE
     KRFREQFEYD KEITVINTAV ACSSNSRNGI FDLPITPGEE LQVIDTTEEN LVICRNSKGK
     YGYVLIEHLD FKHQGWSP
//