ID M3YAK2_MUSPF Unreviewed; 789 AA.
AC M3YAK2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Zinc finger protein 606 {ECO:0000313|Ensembl:ENSMPUP00000008359.1, ECO:0000313|RefSeq:XP_004780545.1, ECO:0000313|RefSeq:XP_004780546.1};
GN Name=ZNF606 {ECO:0000313|Ensembl:ENSMPUP00000008359.1,
GN ECO:0000313|RefSeq:XP_004780545.1, ECO:0000313|RefSeq:XP_004780546.1,
GN ECO:0000313|RefSeq:XP_044933237.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000008359.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000008359.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004780545.1, ECO:0000313|RefSeq:XP_004780546.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004780545.1,
RC ECO:0000313|RefSeq:XP_004780546.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AEYP01100334; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01100335; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01100336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004780545.1; XM_004780488.3.
DR RefSeq; XP_004780546.1; XM_004780489.3.
DR RefSeq; XP_044933237.1; XM_045077302.1.
DR Ensembl; ENSMPUT00000008494.1; ENSMPUP00000008359.1; ENSMPUG00000008423.1.
DR GeneID; 101673195; -.
DR KEGG; mpuf:101673195; -.
DR CTD; 80095; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000161820; -.
DR HOGENOM; CLU_002678_44_5_1; -.
DR OMA; FGDHKGM; -.
DR OrthoDB; 5247553at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 16.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24399:SF54; GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED; 1.
DR PANTHER; PTHR24399; ZINC FINGER AND BTB DOMAIN-CONTAINING; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 13.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 15.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 9.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 13.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 15.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 60..131
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 315..342
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 398..425
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 426..453
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 454..481
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 482..509
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 510..537
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 538..565
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 566..593
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 594..621
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 622..649
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 650..677
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 678..705
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 706..733
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 734..761
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 762..789
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 789 AA; 91447 MW; 0C87C61D0C95CFAE CRC64;
MAAINPWASW GVLTDQSWGI AAVDPWASWA LCPQDCHVEE NAKEERRATG FPTAQIQEPV
TFKDVAVDFT QEEWGQLDSV QRTLYRDVML ETYGHLLSVG NHIAKPEVIS LLEQGEEPWS
VEQAYPQSTC PEWMRNLERK ALIPTQSVLE EEQSHSMKLE RYIWDDPLFS RLEVLGCKDQ
LEMYHMNQST AMRQMVFMQK QVLSQRGSEF CELGAEYSQN LNFVPSQRVS QIEHFYKPGT
NAESWRCNSA IMYADKITCG NLDYDKACHQ SIQPIQPEKI QTGDNLLKCP DAVKSFNHIL
HFGDRKGMHT GEKLYEYKEC HQIFNQSPSY NEHPQLHIGE NQYDYKEYEN IFYFSSFMEH
PKIGTVEKAY KYNEWEKVFG YDSFLTQHTS TYTSEKPYEY NECGTSFIWS SYLIQHKKTH
TGEKPYECDK CGKVFRNRSA LTKHERTHTG IKPYECNKCG KAFSWNSHLI VHKRIHTGEK
PYVCNECGKS FNWNSHLIGH QRTHTGEKPF ECTECGKSFS WSSHLIAHMR MHTGEKPFKC
DECEKAFRDY SALSKHERTH SGAKPYKCTE CGKSFSWSSH LIAHQRTHTG EKPYNCQECG
KAFRERSALT KHEIIHSGIK PYECNKCGKS CSQMAHLVRH QRTHTGEKPY ECNKCGKSFS
QSCHLVAHRR IHTGEKPYKC NQCERSFNCS SHLIAHRRTH TGEKPYRCNE CGKAFNESSS
LIVHLRNHTG EKPYKCNHCE KAFCKNSSLI IHQRMHSGEK RFICSDCGKA FSGHSALLQH
QRNHSEEKL
//
