ID   M3YBR8_MUSPF            Unreviewed;       473 AA.
AC   M3YBR8;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Interferon regulatory factor 7 {ECO:0000313|Ensembl:ENSMPUP00000008775.1};
GN   Name=IRF7 {ECO:0000313|Ensembl:ENSMPUP00000008775.1};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000008775.1};
RN   [1] {ECO:0000313|Ensembl:ENSMPUP00000008775.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2023) to UniProtKB.
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DR   EMBL; AEYP01101511; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M3YBR8; -.
DR   STRING; 9669.ENSMPUP00000008775; -.
DR   Ensembl; ENSMPUT00000008919.1; ENSMPUP00000008775.1; ENSMPUG00000008845.1.
DR   eggNOG; ENOG502R2I9; Eukaryota.
DR   GeneTree; ENSGT00940000160931; -.
DR   HOGENOM; CLU_031544_2_0_1; -.
DR   InParanoid; M3YBR8; -.
DR   OMA; HEIAQME; -.
DR   GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0002753; P:cytoplasmic pattern recognition receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IEA:Ensembl.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IEA:Ensembl.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0002819; P:regulation of adaptive immune response; IEA:Ensembl.
DR   GO; GO:0034124; P:regulation of MyD88-dependent toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0034127; P:regulation of MyD88-independent toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon-mediated signaling pathway; IEA:Ensembl.
DR   CDD; cd00103; IRF; 1.
DR   Gene3D; 2.60.200.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR019817; Interferon_reg_fac_CS.
DR   InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR   InterPro; IPR019471; Interferon_reg_factor-3.
DR   InterPro; IPR017855; SMAD-like_dom_sf.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR   PANTHER; PTHR11949:SF2; INTERFERON REGULATORY FACTOR 7; 1.
DR   Pfam; PF00605; IRF; 1.
DR   Pfam; PF10401; IRF-3; 1.
DR   PRINTS; PR00267; INTFRNREGFCT.
DR   SMART; SM00348; IRF; 1.
DR   SMART; SM01243; IRF-3; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00601; IRF_1; 1.
DR   PROSITE; PS51507; IRF_2; 1.
PE   4: Predicted;
FT   DOMAIN          11..129
FT                   /note="IRF tryptophan pentad repeat"
FT                   /evidence="ECO:0000259|PROSITE:PS51507"
SQ   SEQUENCE   473 AA;  52038 MW;  8A87D200AB341FC7 CRC64;
     AGRPARRRPP RLLFGDWLLG EVSSGRYEGL RWLDAARTRF RVPWKHFSRK DLGEADSRIF
     KAWAVARGRW PPSSSEGRGG GDQLALEGAL RAVWKTNFRC ALHSTQRFVM LQDNSGDPAD
     PHKVYALSFE PAETGAGTQQ GEVALEDALP LMGELPGPCL AGDAAERPGL GLSPELGAPS
     PPFGAADSAG DLLLQALEQS CLEAHLLEAA WVGDPVPPEA PDAGLARVLE PWQPPPEVEP
     CPGVAAEPGS HREPSLRALD VTIMYKGRTV LQEVVWRPSF VFLYGSPGPA TTATEPQHVA
     FPSPAELPDQ KQMHYTEKLL QHVAPGLQLE LRGCRLWARR RGKCKVYWEV GGPLGSASPS
     TPPRLLQRNQ DTPIFDFSTF FREMMEFRAR RRPGSPHYTI YLGFGQDLSA GRPKEKSLVL
     VKLEPWLCRA HLEYVQREGV SSLDSSSLGL CLSSSNSLYE DLECFLMEVQ QPA
//