ID M3YE71_MUSPF Unreviewed; 404 AA.
AC M3YE71;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Acyl-CoA thioesterase 6 {ECO:0000313|Ensembl:ENSMPUP00000009628.1};
GN Name=ACOT6 {ECO:0000313|Ensembl:ENSMPUP00000009628.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000009628.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000009628.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR EMBL; AEYP01004753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01004754; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YE71; -.
DR STRING; 9669.ENSMPUP00000009628; -.
DR Ensembl; ENSMPUT00000009784.1; ENSMPUP00000009628.1; ENSMPUG00000009704.1.
DR eggNOG; ENOG502QQ8Z; Eukaryota.
DR GeneTree; ENSGT01010000222336; -.
DR HOGENOM; CLU_029849_4_0_1; -.
DR InParanoid; M3YE71; -.
DR OMA; GICEIPL; -.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824:SF17; ACYL-COENZYME A THIOESTERASE 6; 1.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR Pfam; PF08840; BAAT_C; 1.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
FT DOMAIN 18..83
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 187..394
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
FT ACT_SITE 215
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 309
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 343
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ SEQUENCE 404 AA; 44090 MW; 5D26179EC7E596DB CRC64;
IRMPATWILE PAGRCSWDEP VRIAVHGLAP RQPVTLRASL RDEKGALFRA HARYEADAGG
LLDLERAPAL GGSFVGLEPM GLLSFAVELE VLDGHEPDAG RVLGRAVHER EFLRPGVRRE
PVRAGGLRAT LFLPPGAGPF PGIIDLFGSG GGLCEYRASL LAGHGFAVLA LAYFRFEDLP
ENLEALHLEY FEEAVNFMLQ HPQVKGPNVG LLGFSKGGDL CLSMASFLKG ITATVLINTC
VANTIASLHY KDMIIPSLGS DPGRCTINES GHLHFMDVWD NPLEEPNYPS IIPVERAQGP
FLFIVGMDDQ DWKSPVYAQI ASERLQAHGK DRPQIICYPG TGHCIDPPYF PPCRASVHTV
LGQAIVHGGE PKAQSRAQVD AWQQIQTFFH KHLSGKKFAQ SSKI
//
