ID M3YF39_MUSPF Unreviewed; 296 AA.
AC M3YF39;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN Name=LOC101675922 {ECO:0000313|RefSeq:XP_004779056.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000009946.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000009946.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004779056.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004779056.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRIM/RBCC family.
CC {ECO:0000256|ARBA:ARBA00008518}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEYP01095768; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01095769; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004779056.1; XM_004778999.3.
DR RefSeq; XP_012904700.1; XM_013049246.1.
DR STRING; 9669.ENSMPUP00000009946; -.
DR Ensembl; ENSMPUT00000010106.1; ENSMPUP00000009946.1; ENSMPUG00000010021.1.
DR GeneID; 101675922; -.
DR KEGG; mpuf:101675922; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000154647; -.
DR HOGENOM; CLU_013137_6_1_1; -.
DR OMA; IIATIEC; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19761; Bbox2_TRIM5-like; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR020457; Znf_B-box_chordata.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF416; TRIPARTITE MOTIF-CONTAINING PROTEIN 5; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01406; BBOXZNFINGER.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 15..61
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 93..134
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT COILED 138..208
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 296 AA; 34445 MW; B655D96C3E3234A6 CRC64;
MASKLLTNIK EEVTCPICLD LLKEPLSLGC GHSFCKACIT AANKESKTSQ EEKSTSCPVC
QFHYCAKELR PNWHVANIVE RFREVKVSSE EGQKRNLCER HEEKLLLFCK KDGKVLCWVC
ERSQEHRGHQ TVPMDEAVQE YQEKLQTALQ KVIKEQQEAE MLNANLREQR TSWKNHMQNE
KKYIHTKFKK LKTMLEREEK NIVQMLDNEE ETILNSFVSV EDEVAQHSQI VKDLISELEH
RLQGSTVGML QDVHSVMERS KNLSLKKQKA FLKEQKKVSG IPDLKELMQL FIDLVF
//
