ID   M3YF93_MUSPF            Unreviewed;       692 AA.
AC   M3YF93;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Erythrocyte membrane protein band 4.2 {ECO:0000313|Ensembl:ENSMPUP00000010000.1};
DE   SubName: Full=Protein 4.2 {ECO:0000313|RefSeq:XP_004751276.1};
GN   Name=EPB42 {ECO:0000313|Ensembl:ENSMPUP00000010000.1,
GN   ECO:0000313|RefSeq:XP_004751276.1};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000010000.1};
RN   [1] {ECO:0000313|Ensembl:ENSMPUP00000010000.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2023) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_004751276.1}
RP   IDENTIFICATION.
RC   TISSUE=Brain {ECO:0000313|RefSeq:XP_004751276.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transglutaminase superfamily.
CC       Transglutaminase family. {ECO:0000256|ARBA:ARBA00005968}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AEYP01028369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_004751276.1; XM_004751219.3.
DR   STRING; 9669.ENSMPUP00000010000; -.
DR   Ensembl; ENSMPUT00000010160.1; ENSMPUP00000010000.1; ENSMPUG00000010075.1.
DR   GeneID; 101682468; -.
DR   KEGG; mpuf:101682468; -.
DR   CTD; 2038; -.
DR   eggNOG; ENOG502R9T9; Eukaryota.
DR   GeneTree; ENSGT01050000244866; -.
DR   HOGENOM; CLU_013435_3_0_1; -.
DR   OMA; NPWGRED; -.
DR   OrthoDB; 5344745at2759; -.
DR   Proteomes; UP000000715; Unplaced.
DR   GO; GO:0170014; C:ankyrin-1 complex; IEA:Ensembl.
DR   GO; GO:0030863; C:cortical cytoskeleton; IEA:Ensembl.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0020027; P:hemoglobin metabolic process; IEA:Ensembl.
DR   GO; GO:0060586; P:multicellular organismal-level iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR036985; Transglutaminase-like_sf.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR008958; Transglutaminase_C.
DR   InterPro; IPR036238; Transglutaminase_C_sf.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   PANTHER; PTHR11590:SF44; PROTEIN 4.2; 1.
DR   PANTHER; PTHR11590; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF00927; Transglut_C; 2.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF49309; Transglutaminase, two C-terminal domains; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000715}.
FT   DOMAIN          260..353
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
SQ   SEQUENCE   692 AA;  76984 MW;  BD121A57D065E0D0 CRC64;
     MGQALGIKNC DFQAAKNNEE HHTKAISSRH LIVRRGQPFT IILHFQAPVY AFTSNLKKVA
     LIAQTGEHPS KANKTQAIFP ISHLGDQKWW NAAVEDRDDQ SWAISVTAPA DAIIGHYSLL
     LQVLGKKQLH LGQFTLLFNP WAREDAVFLK KESQRREYVL NQNGLIYLGT AECFHAEPWD
     FGQFESSVIN LSLRLLSVDK QVEEWGNPEH VACILGALLH ALKEKSVLPP TKAATAQEGA
     LLSKRRGSVP ILRQWVTGQG RPVYDSQAWV FAAVACTVLR CLGIPARVIT TFTSAQGTGG
     RLLVDEYYNE EGLQNGEGQG GRIWIFQTST ECWMTRPALP PGYDGWQILY PCVSNGGGVL
     GSCDLTPVKA VKEGTLSLTP GVSDLFAAVN ASCVVWKCRE DGALELTNSN TKYVGNNIST
     KGVGSNRCED ITQNYKYPEG SLQEKEVLEK VQEERMRHEK DSGIHPPSLK TAELLHIFLE
     VPCSLNLGGE AQYSVKLVNL SDQEKAVQLT SALQAIYYNG ILAAELWKRK QSLMLGPKAN
     IITSNLSFSH FEQSPPENSF LRLTVMATAM HSESSLSCFA QEDIVICRPH LTIEMPETAE
     QYQLLKASVQ LHNFLDAPLK DCVISLFGRG LIHRERRYRL ASVWPGNILY TEFQFTPTQV
     GLQRLTVEMD CDMFQNVTNY RNITVEAPEL PA
//