ID M3YGG9_MUSPF Unreviewed; 1168 AA.
AC M3YGG9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=DCC netrin 1 receptor {ECO:0000313|Ensembl:ENSMPUP00000010426.1};
GN Name=DCC {ECO:0000313|Ensembl:ENSMPUP00000010426.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000010426.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000010426.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. DCC family.
CC {ECO:0000256|ARBA:ARBA00009588}.
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DR EMBL; AEYP01097936; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097937; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097938; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097939; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097940; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097942; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097943; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097944; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01097945; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YGG9; -.
DR STRING; 9669.ENSMPUP00000010426; -.
DR Ensembl; ENSMPUT00000010594.1; ENSMPUP00000010426.1; ENSMPUG00000010503.1.
DR eggNOG; KOG4221; Eukaryota.
DR GeneTree; ENSGT00940000158867; -.
DR HOGENOM; CLU_004256_0_0_1; -.
DR InParanoid; M3YGG9; -.
DR OMA; KPEAVYT; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 6.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR010560; Neogenin_C.
DR PANTHER; PTHR44170:SF8; NETRIN RECEPTOR DCC; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF06583; Neogenin_C; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 821..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..49
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 54..139
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 154..247
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 253..343
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 348..441
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 451..544
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 569..665
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 670..767
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 849..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1014..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 903..943
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1168 AA; 127977 MW; 00D7381187C27CB2 CRC64;
MPVSYRSKKY SLLGGSNLLI SNVTDDDSGT YTCVVTYKNE NISASAELTV LVPPWFLNHP
SNLYAYESMD IEFECSVSGK PVPTVNWMKN GDVVLPSDYF QIVGGSNLRI LGVVKSDEGF
YQCVAENEAG NVQTSAQLIV PKPAIPSSNV LPSAPRDVVP VLVSSRFVRL SWRPPAEAKG
NIQTFTVFFS REGDNRERAL NTSQPGSLQL TVGNLKPEAM YTFRVVAYNE WGPGESSQPI
KVATQPELQV PGPVENLQAV STSPTSILIT WEPPAYANGP VQGYRLFCTE VSTGKEQNIE
VDGLSYKLEG LKKFTEYTLR FLAYNRYGPG VSTDDITVVT LSDVPSAPPQ NVSLEVVNSR
SIKVSWLPPP SGTQNGFITG YKIRHRKTTR RGEMETLEPN NLWYLFTGLE KGSQYSFQVS
AMTVNGTGPP SNWYTAETPE NDLDESQVPD QPSSLHVRPQ TNCIIMSWTP PLNPNIVVRG
YIIGYGVGSP YAETVRVDSK QRYYSIERLE SSSHYVISLK AFNNAGEGVP LYESATTRSI
TDPTDPVDYY PLLDDFPTSV PDVSTPMLPP VGVQAVALTY DAVRVSWADN SVPKNQKTSE
VRLYTVRWRT SFSANAKYKS EDTTSLSYTA TGLKPNTMYE FSVMVTKNRR SSTWSMTAHA
TTYEAAPTSA PKDLTVITRE GKPRTVIVSW QPPLEANGKI TAYILFYTLD KNIPIDDWVM
ETISGDRLTH QIMDLNLDTM YYFRIQARNA KGVGPLSDPI LFRTLKVEHP DKMANDQGRH
GDGGYWPVDT NLIDRSTLNE PPIGQMHPPH GSVTPQKNSN LLVITVITVG VITVLVVVIV
AVICTRRSSA QQRKKRATHS VGKRKGSQKD LRPPDLWIHH EEMEMKNIEK PSGADPAGRD
SPIQSCQDLT PVSHSQSETQ LGSKSTSHSG QDTEEAGSSM STLERSLAAR RATRAKLMIP
MDAQSNNPAV VSAIPVPTLE SAQYPGILPS PTCGYPHPQF TLRPVPFPTL SVDRGFGTGK
TVSEGPASQQ PPLLPPAQPE HPSTEEAPSR TIPTACVRPT HPLRSFANPL LPPPMSAIEP
KVPYTPLLSQ PGPTLPKTHV KTASLGLAGK ARSPLLPVSV PTAPEVSEES HKATEDPANV
YEQDDLSEQM ASLEGLMKQL NAITGSAF
//
