ID M3YGX1_MUSPF Unreviewed; 268 AA.
AC M3YGX1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit D {ECO:0000256|ARBA:ARBA00018992};
DE AltName: Full=TATA box-binding protein-associated factor 1D {ECO:0000256|ARBA:ARBA00032499};
DE AltName: Full=Transcription initiation factor SL1/TIF-IB subunit D {ECO:0000256|ARBA:ARBA00030353};
GN Name=TAF1D {ECO:0000313|Ensembl:ENSMPUP00000010578.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000010578.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000010578.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- FUNCTION: Component of the transcription factor SL1/TIF-IB complex,
CC which is involved in the assembly of the PIC (preinitiation complex)
CC during RNA polymerase I-dependent transcription. The rate of PIC
CC formation probably is primarily dependent on the rate of association of
CC SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in
CC stabilization of nucleolar transcription factor 1/UBTF on rDNA.
CC Formation of SL1/TIF-IB excludes the association of TBP with TFIID
CC subunits. {ECO:0000256|ARBA:ARBA00025110}.
CC -!- SUBUNIT: Component of the transcription factor SL1/TIF-IB complex,
CC composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts
CC with UBTF. {ECO:0000256|ARBA:ARBA00025940}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AEYP01058707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01058708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YGX1; -.
DR STRING; 9669.ENSMPUP00000010578; -.
DR Ensembl; ENSMPUT00000010750.1; ENSMPUP00000010578.1; ENSMPUG00000010659.1.
DR eggNOG; ENOG502SQMW; Eukaryota.
DR GeneTree; ENSGT00390000009061; -.
DR HOGENOM; CLU_071614_1_0_1; -.
DR InParanoid; M3YGX1; -.
DR OMA; PLCSLID; -.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0072686; C:mitotic spindle; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005668; C:RNA polymerase transcription factor SL1 complex; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR027976; TAF1D.
DR PANTHER; PTHR14562; TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D; 1.
DR PANTHER; PTHR14562:SF3; TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D; 1.
DR Pfam; PF15333; TAF1D; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..106
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 268 AA; 31030 MW; CDAC0C7C721BE459 CRC64;
MASNSAVEID SESDNSSGSS LFKTQCVPYS PKRVQRNRTR KFVHLPEVAQ ARDSSSDDSF
EPRPLTLKAI FERFKNRKRK RKKKKYKPTG RPKGRPKGRK TSRRSQINKK QVQDKGSGFP
FLESESARKP LPWRKILTFE QAVARGFFNY LEKLKYEYYL KESLKQMNVG EDLEKEDFDS
RRYKYLDDDG ALSPIEESET EDGSATNVEQ NGECDIKLVA FHLNTMSGIK GTSYTFRGEY
DLNSLIFRGC LKLRTRQIHT QTLNRALK
//
