ID M3YH87_MUSPF Unreviewed; 517 AA.
AC M3YH87;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Gamma-1-syntrophin {ECO:0000313|RefSeq:XP_012902859.1};
DE SubName: Full=Syntrophin gamma 1 {ECO:0000313|Ensembl:ENSMPUP00000010694.1};
GN Name=SNTG1 {ECO:0000313|Ensembl:ENSMPUP00000010694.1,
GN ECO:0000313|RefSeq:XP_012902859.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000010694.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000010694.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_012902859.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_012902859.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the syntrophin family.
CC {ECO:0000256|ARBA:ARBA00010798}.
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DR EMBL; AEYP01087417; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087419; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087420; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087421; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087422; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087424; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087425; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01087426; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012902859.1; XM_013047405.2.
DR STRING; 9669.ENSMPUP00000010694; -.
DR Ensembl; ENSMPUT00000010873.1; ENSMPUP00000010694.1; ENSMPUG00000010782.1.
DR GeneID; 101683458; -.
DR KEGG; mpuf:101683458; -.
DR CTD; 54212; -.
DR eggNOG; KOG3549; Eukaryota.
DR GeneTree; ENSGT00950000182863; -.
DR HOGENOM; CLU_039445_0_0_1; -.
DR OMA; YVTRYLW; -.
DR OrthoDB; 2906429at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0032587; C:ruffle membrane; IEA:Ensembl.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd00821; PH; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR015482; Syntrophin.
DR PANTHER; PTHR10554:SF2; GAMMA-1-SYNTROPHIN; 1.
DR PANTHER; PTHR10554; SYNTROPHIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715}.
FT DOMAIN 57..140
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 283..390
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 517 AA; 58008 MW; 8D78C071CDF1D654 CRC64;
MDFRTACEET KTGICLLQDG NQEPFKVRLH LAKDILMIQE QDVICVSGEP FYSGERTVTI
RRQTVGGFGL SIKGGAEHNI PVVISKISKE QRAELSGLLF IGDAILQING INVRKCRHEE
VVQVLRNAGE EVTLTVSFLK RSPAFLKLPL NEDCACAPSD QSSGTSSPLC DSGLHLNYHP
NNTDTLSCSS WPTSPGLRWE KRWCDLRLIP LLHSRFSQYV PGTDLSRQNA FQVIAVDGVC
SGIIQCLSAE DCVDWLQAIA TNISNLTKHN IKKINRNFPV NQQIVYMGWC EAREQDPLQD
RVYSPTFLAL RGSCLYKFLA PPVTTWDWTR AEKTFSVYEI MCKILKDSDL LDRRKHCFTV
QSESGEDLYF SVELESDLAQ WERAFQTATF LEVERIQCKT YACVLESHLM GLTIDFSTGF
ICFDAATKAI LWRYKFSQLK GSSDDGKSKI KFLFQNPDTK QIEAKELEFS NLFAVLHCIH
SFFAAKVACL DPLFLGNQAT ASAAASSATT SKTKYTT
//
