ID   M3YHC8_MUSPF            Unreviewed;       837 AA.
AC   M3YHC8;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Neural cell adhesion molecule 2 {ECO:0000313|Ensembl:ENSMPUP00000010735.1};
GN   Name=NCAM2 {ECO:0000313|Ensembl:ENSMPUP00000010735.1};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000010735.1};
RN   [1] {ECO:0000313|Ensembl:ENSMPUP00000010735.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2023) to UniProtKB.
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DR   EMBL; AEYP01074857; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01074858; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01074859; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01074860; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01074861; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M3YHC8; -.
DR   STRING; 9669.ENSMPUP00000010735; -.
DR   Ensembl; ENSMPUT00000010914.1; ENSMPUP00000010735.1; ENSMPUG00000010823.1.
DR   eggNOG; KOG3510; Eukaryota.
DR   GeneTree; ENSGT00940000157860; -.
DR   HOGENOM; CLU_010961_1_0_1; -.
DR   InParanoid; M3YHC8; -.
DR   OMA; XPPAITM; -.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   CDD; cd00063; FN3; 2.
DR   CDD; cd00096; Ig; 1.
DR   CDD; cd20970; IgI_1_MuSK; 1.
DR   CDD; cd05866; IgI_1_NCAM-2; 1.
DR   CDD; cd05870; IgI_NCAM-2; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR009138; Neural_cell_adh.
DR   PANTHER; PTHR12231; CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN; 1.
DR   PANTHER; PTHR12231:SF231; NEURAL CELL ADHESION MOLECULE 2; 1.
DR   Pfam; PF00041; fn3; 2.
DR   Pfam; PF07679; I-set; 4.
DR   Pfam; PF13927; Ig_3; 1.
DR   PRINTS; PR01838; NCAMFAMILY.
DR   SMART; SM00060; FN3; 2.
DR   SMART; SM00409; IG; 5.
DR   SMART; SM00408; IGc2; 5.
DR   SMART; SM00406; IGv; 3.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 5.
DR   PROSITE; PS50853; FN3; 2.
DR   PROSITE; PS50835; IG_LIKE; 5.
PE   4: Predicted;
KW   Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW   Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        695..718
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          21..108
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          113..186
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          208..297
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          302..396
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          401..491
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          498..591
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          593..688
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   REGION          764..817
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        764..784
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        800..815
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   837 AA;  93068 MW;  FAD87F95DCA5D832 CRC64;
     MGSIKKHILK NLNMSSKSSL LQVTISLSKV ELSVGESKFF TCTAIGEPES IDWYNPQGEK
     IISTQRVAVQ KEGVRSRLTI YNANIEDAGI YRCQATDAKG QTQEATVVLE IYQKLTFKEV
     VSPQEFKQGE DAEVVCRVSS SPAPAVSWLY HNEEVTAISD NRFAMLANNN LQILNINKSD
     EGIYRCEGRV EARGEIDFRD IIVIVNVPPA ITMPQKSFNA TAERGEEMTF SCRASGSPEP
     SISWYRNGKF IEENEKYILK GSNTELTVRN IINSDGGPYI CRATNKAGED EKQAFLQVFV
     QPHIIQLKNE TTYENGQVTL ICEAEGEPIP EITWKRAVDG ITFSEGDKSP DGRIEVKGQH
     GSSSLHIQDV KLSDSGRYDC EAASRIGGHQ KSMYLDIEYA PKFISNQTIY YSWEGNPINI
     SCDVKSNPPA SVHWRKEKLV LPAKNITNLK TYSAGRKMIL EIAPTSDNDF GRYNCTATNR
     IGTRFQEYIL ALADVPSSPY GVKIIELSQT TAKVSFNKPD SHGGVPIHHY QVDVKEVASE
     TWKIVRSHGV QTMVVLSNLE PNTTYEIRVA AVNGKGQGDY SKIEIFQTLP VREPSPPAIH
     GQPSSGKSFK LSITKQDDGG APILEYIVKY RSKDKEDQWL EKKVQGNKDH IILEHLQWTM
     GYEVQITAAN RLGYSEPTVY EFSMPPKPNI IKDTLFNGLG LGAVIGLGVA ALLLILVVTD
     VSCFFIRQCG LLMCITRRMC GKKSGSSGKS KELEEGKAAY LKDGSKEPIV EMRTEDERIT
     NHEDGSPVNE PNETTPLTEP EKLPLKEENG KEVLNPETIE IKVSNDIIQS KEDDSKA
//