ID M3YHT4_MUSPF Unreviewed; 798 AA.
AC M3YHT4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 21 {ECO:0000256|ARBA:ARBA00020102};
DE AltName: Full=Coiled-coil domain-containing protein 128 {ECO:0000256|ARBA:ARBA00031617};
DE AltName: Full=KLRAQ motif-containing protein 1 {ECO:0000256|ARBA:ARBA00031361};
GN Name=PPP1R21 {ECO:0000313|Ensembl:ENSMPUP00000010891.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000010891.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000010891.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
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DR EMBL; AEYP01032780; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01032781; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01032782; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01032783; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01032784; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YHT4; -.
DR STRING; 9669.ENSMPUP00000010891; -.
DR Ensembl; ENSMPUT00000011073.1; ENSMPUP00000010891.1; ENSMPUG00000010980.1.
DR eggNOG; KOG4421; Eukaryota.
DR GeneTree; ENSGT00390000006820; -.
DR HOGENOM; CLU_022372_0_0_1; -.
DR InParanoid; M3YHT4; -.
DR OMA; NLHTYTE; -.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR040024; PPP1R21.
DR InterPro; IPR049372; PPP1R21_C.
DR InterPro; IPR019343; PPP1R21_N.
DR InterPro; IPR019348; PPP1R21_six_helix.
DR PANTHER; PTHR21448:SF0; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21; 1.
DR PANTHER; PTHR21448; SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED; 1.
DR Pfam; PF10205; KLRAQ; 1.
DR Pfam; PF21636; PPP1R21_C; 1.
DR Pfam; PF10212; PPP1R21_helical; 1.
DR SMART; SM01254; KLRAQ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753}.
FT DOMAIN 37..130
FT /note="Protein phosphatase 1 regulatory subunit 21 N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM01254"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 778..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 56..90
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 180..214
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 576..610
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 714..748
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 798 AA; 90070 MW; E1FC7B640134B4EA CRC64;
MGAGTGERVP FEGRSERRRF ASCLPDGITP ATTESLQLRA QNQVLKKGVV DEQANSAALK
EQLKMKDQSL RKLQQEMDSL TFRNLQLAKR VELLQDELAL SEPRGKKNKK SGESSSHLSQ
EQKSVFDEDL QKKIEENERL HIQFFEADEQ HKHVEAELRS RLATLEMEAT QHQAVVDGLT
RKYMETIEKL QNDKAKLEVK SQTLEKEAKE CRLRTEECQL QLKNLHDDLS GRLEESLSII
TEKVPFNDTK YSQYNALNVP LHNRRHQLKM RDIAGQALAF VQDLVMALLN FHTYTEQRIQ
IFPIDSAIEP ISPLNQKFSQ YLHENASYVR PLEEGMLHLF ESITEDTVTV LETTVKLKTF
SEHLTSYICF LKKILPYQLK SLEEECESSL CTSALRARNL ELSQDMKKMT AVFEKLETYI
HLLALPSTEP DGLLRTNYGS VLTNVGAALH GFHDVVKDIS KHYSQKATIE HELPTATQKL
ITTNDCILSS LVALTNGAGK IASFFSNNVD CFNASLSYGP KAASGFISPL SAECMLQYKR
KAAAYMKALR KPLLESVPYE EALANRRVLL SSTESREGLA QQVQQSLEKI SKLEQEKEHW
MLEAQLAKIK LEKENQRIAD KLRSTSSGQG LGLAQENATG VNAAGREEAS AKAVLEPAHS
TSLIGVLTRT SDNEVPDVES REDLIKNHYM ARIVELTSQL QLADSKSVHF YAECRALSKR
LALAEKSKDA LTEDMKVAGQ NISRLQDELT TTKRSYEDQL SMMSDHLCSM NETLSKQREE
IDTLKMSSKG NSKKNKSR
//
