ID M3YJB6_MUSPF Unreviewed; 407 AA.
AC M3YJB6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=Sorting nexin {ECO:0000256|PIRNR:PIRNR036924};
GN Name=SNX32 {ECO:0000313|Ensembl:ENSMPUP00000011423.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000011423.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000011423.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- FUNCTION: Involved in several stages of intracellular trafficking.
CC {ECO:0000256|PIRNR:PIRNR036924}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883, ECO:0000256|PIRNR:PIRNR036924}.
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DR EMBL; AEYP01074190; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YJB6; -.
DR STRING; 9669.ENSMPUP00000011423; -.
DR Ensembl; ENSMPUT00000011612.1; ENSMPUP00000011423.1; ENSMPUG00000011514.1.
DR eggNOG; KOG1660; Eukaryota.
DR GeneTree; ENSGT00940000162773; -.
DR HOGENOM; CLU_040966_0_0_1; -.
DR InParanoid; M3YJB6; -.
DR OMA; ETHQQLC; -.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd07621; BAR_SNX5_6; 1.
DR CDD; cd06892; PX_SNX5_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR014637; SNX5/SNX6/SNX32.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR45850; SORTING NEXIN FAMILY MEMBER; 1.
DR PANTHER; PTHR45850:SF3; SORTING NEXIN-32; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR PIRSF; PIRSF036924; Snx5_Snx6; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR036924};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR036924}.
FT DOMAIN 25..173
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 46916 MW; DF5A627B2FF70D48 CRC64;
LVGMPEFSNQ QTSPPQQPSS VSVDLQGDST LQVEISDAVS ERDKVKFTVQ TKSCLPHFAQ
TEFSVVRQHE EFIWLHDAYV ENEEYAGLII PPAPPRPDFE ASREKLQKLG EGDSSITREE
FAKMKQELEA EYLALFKKTV AMHEVFLQRL AAHPTLRRDH NFFVFLEYGQ DLSVRGKNRK
ELLGGFLRNI VKSADEALIT SMSGLKEVDD FFEHERTFLL EYHTRIRDAC LRADRVMHSH
KCLADDFIPI SAALNSLGTQ EVNQLKTSFL KLAELFERLR KLEGRVASDE DLKLSDMLRY
YMRDSQAAKD LLYRRLRALA DYENANKALD KARTRNREVR TAESHQQLCC QRFERLSDSA
KQELMDFKSR RVSSFRKNLI ELAELELKHA KASTLLLRNT LIALKGE
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