ID M3YLD7_MUSPF Unreviewed; 592 AA.
AC M3YLD7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Zinc finger SWIM-type containing 2 {ECO:0000313|Ensembl:ENSMPUP00000012144.1};
GN Name=ZSWIM2 {ECO:0000313|Ensembl:ENSMPUP00000012144.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000012144.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000012144.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
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DR EMBL; AEYP01057852; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YLD7; -.
DR STRING; 9669.ENSMPUP00000012144; -.
DR Ensembl; ENSMPUT00000012344.1; ENSMPUP00000012144.1; ENSMPUG00000012241.1.
DR eggNOG; KOG0800; Eukaryota.
DR GeneTree; ENSGT00390000006826; -.
DR HOGENOM; CLU_029121_0_0_1; -.
DR InParanoid; M3YLD7; -.
DR OMA; RNQKWRS; -.
DR GO; GO:0043621; F:protein self-association; IEA:Ensembl.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR CDD; cd16486; mRING-H2-C3H2C2D_ZSWM2; 1.
DR CDD; cd16494; RING-CH-C4HC3_ZSWM2; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR007527; Znf_SWIM.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR InterPro; IPR039903; Zswim2.
DR PANTHER; PTHR21540:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2; 1.
DR PANTHER; PTHR21540; RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF04434; SWIM; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00184; RING; 2.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS50089; ZF_RING_2; 2.
DR PROSITE; PS50966; ZF_SWIM; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 10..43
FT /note="SWIM-type"
FT /evidence="ECO:0000259|PROSITE:PS50966"
FT DOMAIN 103..155
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 186..237
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 301..342
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 592 AA; 68337 MW; DFC99B04B2912D02 CRC64;
GFLLKMHFPL KVFLGNPHVC NCATFLEGGE LCKHICWVLL KKFKLPRTHE SALQLGLMEG
EISDLLRGIH RVQTPQQETI DETVRIEEDG YIKQKEIDSE DICPICQEGL LEKKLPVTFC
RFGCGNSIHI KCMKILANYQ DRISDTSVLK CPLCRKEFAP LKLILEEFKN SSKLVTAAEK
ERRDKHLGIP CNSCKQCPVE GRCYKCTKCT EFHLCQECFP SRCHPPHAFT FREKRNQRWK
SLEKGSDEIV KYADIRNERE EKMPHFQEKQ GQVYTPKQVV KSLPLLLITK NSKLLAPGYQ
CRLCLKAFHP GQHTRLLPCT HKFHRKCIDS WLFYKCNSCP IDGQVIYNPL IWKDKAVSGH
THPSVSNTNI THLSKQEELE LFIPGTGLVI KRNRLRILPR ITQHNSEKFN TPESPTDTHQ
DIAIDDLFSN KLDDSNSRKL IYEYKISQHF PRYLQDLPTG PFGKMSSQTF LPAIADKNNM
CPTGMETPHI NEKYHTCQSQ KMAKDCKHIN HNPKKTSGAR MREDKKRLDT LLPEDLNLIT
NWGTTKISLS KRYNNCMGKI RQKYSNLSRR PESHPLNIKS PELSFILEGV QL
//
