ID M3YLN8_MUSPF Unreviewed; 208 AA.
AC M3YLN8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Osteoclast-stimulating factor 1 {ECO:0000256|ARBA:ARBA00040640};
GN Name=OSTF1 {ECO:0000313|Ensembl:ENSMPUP00000012245.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000012245.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000012245.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- FUNCTION: Induces bone resorption, acting probably through a signaling
CC cascade which results in the secretion of factor(s) enhancing
CC osteoclast formation and activity. {ECO:0000256|ARBA:ARBA00037432}.
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DR EMBL; AEYP01078459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9669.ENSMPUP00000012245; -.
DR Ensembl; ENSMPUT00000012445.1; ENSMPUP00000012245.1; ENSMPUG00000012340.1.
DR eggNOG; ENOG502QTZB; Eukaryota.
DR GeneTree; ENSGT00920000149159; -.
DR InParanoid; M3YLN8; -.
DR GO; GO:0017124; F:SH3 domain binding; IEA:Ensembl.
DR CDD; cd11772; SH3_OSTF1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24155; OSTEOCLAST-STIMULATING FACTOR 1; 1.
DR PANTHER; PTHR24155:SF10; OSTEOCLAST-STIMULATING FACTOR 1; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR01415; ANKYRIN.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 12..71
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REPEAT 72..104
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 139..171
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 208 AA; 23033 MW; EB5A5925A9FE0701 CRC64;
MSKPPPKPVK PGQVKVFRAL YTFEPRTPDE LYFEEGDIIY ITDMSDTNWW KGTSKGRTGL
IPSNYVAEQA ESIDNPLHEA AKRGNLSWLR ECLDNGVGVN GLDKAGSTAL YWACHGGHKD
VVEVLFTQPN VELNQQNKLG DTALHAAAWK GYADIVQLLL EKGARTDLRN NEKKLALDMA
TNAACXXXXX XXXXXXXXXX XXXXXXXX
//
