ID M3YLW7_MUSPF Unreviewed; 198 AA.
AC M3YLW7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Ferritin {ECO:0000256|RuleBase:RU361145};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000012324.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000012324.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- FUNCTION: Stores iron in a soluble, non-toxic, readily available form.
CC Important for iron homeostasis. Iron is taken up in the ferrous form
CC and deposited as ferric hydroxides after oxidation.
CC {ECO:0000256|RuleBase:RU361145}.
CC -!- SIMILARITY: Belongs to the ferritin family.
CC {ECO:0000256|ARBA:ARBA00007513, ECO:0000256|RuleBase:RU361145}.
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DR EMBL; AEYP01038036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01038037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YLW7; -.
DR STRING; 9669.ENSMPUP00000012324; -.
DR Ensembl; ENSMPUT00000012525.1; ENSMPUP00000012324.1; ENSMPUG00000012418.1.
DR eggNOG; KOG2332; Eukaryota.
DR GeneTree; ENSGT00950000182841; -.
DR HOGENOM; CLU_065681_4_0_1; -.
DR InParanoid; M3YLW7; -.
DR OMA; ETQEWES; -.
DR GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR GO; GO:0006879; P:intracellular iron ion homeostasis; IEA:UniProtKB-KW.
DR GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR CDD; cd01056; Euk_Ferritin; 1.
DR Gene3D; 1.20.1260.10; -; 2.
DR InterPro; IPR001519; Ferritin.
DR InterPro; IPR012347; Ferritin-like.
DR InterPro; IPR009040; Ferritin-like_diiron.
DR InterPro; IPR009078; Ferritin-like_SF.
DR InterPro; IPR014034; Ferritin_CS.
DR InterPro; IPR008331; Ferritin_DPS_dom.
DR PANTHER; PTHR11431; FERRITIN; 1.
DR PANTHER; PTHR11431:SF97; FERRITIN HEAVY POLYPEPTIDE-LIKE 17-RELATED; 1.
DR Pfam; PF00210; Ferritin; 2.
DR SUPFAM; SSF47240; Ferritin-like; 1.
DR PROSITE; PS00204; FERRITIN_2; 1.
DR PROSITE; PS50905; FERRITIN_LIKE; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU361145};
KW Iron storage {ECO:0000256|ARBA:ARBA00022434,
KW ECO:0000256|RuleBase:RU361145};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361145}.
FT DOMAIN 51..198
FT /note="Ferritin-like diiron"
FT /evidence="ECO:0000259|PROSITE:PS50905"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 198 AA; 22766 MW; CB25CADA0728B233 CRC64;
SSFTLGNLRG HHRPRPRRRP PRSPRLRATF AFALVPGPPA MATPLLSQVR QNYHPDCEAA
VNSQISLELY ASYVYLSMAF YFDRDDVALK HFARFFMRRS RKETQHAEKL MELQNQRGGR
LRLRSVNQSL LDLHQLATDK NDAQLCDFLE SHYLHQQVEA IKELGGYVTS LRKMGAPEAG
LAEYLFDKLT LGDSDKKY
//
