ID M3YQL3_MUSPF Unreviewed; 671 AA.
AC M3YQL3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Zinc finger protein 300 {ECO:0000313|Ensembl:ENSMPUP00000013622.1, ECO:0000313|RefSeq:XP_004737858.1};
GN Name=ZNF300 {ECO:0000313|Ensembl:ENSMPUP00000013622.1};
GN Synonyms=LOC101676130 {ECO:0000313|RefSeq:XP_004737858.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000013622.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000013622.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004737858.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004737858.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AEYP01000943; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004737858.1; XM_004737801.3.
DR Ensembl; ENSMPUT00000013839.1; ENSMPUP00000013622.1; ENSMPUG00000013725.1.
DR GeneID; 101676130; -.
DR KEGG; mpuf:101676130; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000162678; -.
DR HOGENOM; CLU_002678_44_5_1; -.
DR OMA; CNDNEHG; -.
DR OrthoDB; 4775093at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 12.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24399:SF66; NOVEL KRAB BOX AND ZINC FINGER, C2H2 TYPE DOMAIN CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24399; ZINC FINGER AND BTB DOMAIN-CONTAINING; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 12.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 12.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 72..143
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 303..332
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 333..360
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 361..388
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 389..416
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 417..444
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 445..472
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 473..500
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 501..528
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 529..556
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 557..584
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 585..612
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 613..640
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 641..668
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 671 AA; 76479 MW; 265A5FD35992F23A CRC64;
MITEPQGRRR ARAISFDSAW KTAHKTDSLS WEHSVPLNQF SLVCMTPPGA EKNRPGICPF
RREQKMKSQA LVSFKDVAVD FTQEEWQQLD PAQRTLYRDV MLENFSHLVS MGYPVSKPDV
ISKLEQGEDP WIIKRDMPDW IYLDENQADG RQDRKSNLDN TKSCILGSVS FRNNILKGVT
KDGSFYSILK VSQDGGQLQR CQENQDRLFR QVAVINNKTV TVESGHKYNP LGKIFHECIE
PDTLRQRSHN YDVFKKNLKY NVDLHSCNKS NSRKNPDESF GCGKSSSHGA SDSNLEIIHN
GVMPCNNNQC GNIFNSKQSL IQYHNVETKE KTCVCITCGK AFAKKSQLIV HQRIHTGKKP
YDCGACGKAF SEKFHLIVHQ RTHTGEKPYE CSECGKAFSQ KSSLIIHQRV HTGEKPYQCS
ECGKAFSQKS PLIIHQRIHT GEKPYECREC GKAFSQKSQL IIHHRAHTGE KPYECTECGK
AFCEKSHLII HKRIHTGEKP YKCAQCEEAF SRKTELITHQ LIHTGEKPYE CTECGKTFSR
KSQLIIHQRT HTGEKPYKCS ECGKAFCQKS HLIGHQRIHT GEKPYICSEC GKAFSQKSHL
PGHQRIHTGE KPYVCAECGK AFSQKSDLVL HRRIHTGERP YRCTVCGKAF IQKSQLTVHQ
RIHNGGKIIM N
//
