ID M3YTP9_MUSPF Unreviewed; 703 AA.
AC M3YTP9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Collagen type VIII alpha 2 chain {ECO:0000313|Ensembl:ENSMPUP00000014709.1};
GN Name=COL8A2 {ECO:0000313|Ensembl:ENSMPUP00000014709.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000014709.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000014709.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEYP01007750; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004740849.1; XM_004740792.2.
DR AlphaFoldDB; M3YTP9; -.
DR STRING; 9669.ENSMPUP00000014709; -.
DR Ensembl; ENSMPUT00000014942.1; ENSMPUP00000014709.1; ENSMPUG00000014818.1.
DR KEGG; mpuf:101677038; -.
DR eggNOG; ENOG502QRST; Eukaryota.
DR GeneTree; ENSGT00940000154317; -.
DR HOGENOM; CLU_001074_21_0_1; -.
DR InParanoid; M3YTP9; -.
DR OMA; IPHMKYM; -.
DR OrthoDB; 4272636at2759; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR GO; GO:0001935; P:endothelial cell proliferation; IEA:Ensembl.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF33; EMI DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 2.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..703
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004045267"
FT DOMAIN 570..703
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 70..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..100
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..197
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..234
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..426
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..533
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 67206 MW; 9A2ABB671CD6C266 CRC64;
MRGALPPLSS LLLLLLLLLL ECGPRAATGG GAGGAAGYAP VKYVQPMHKG PVGPPFREGK
GQYLEMPLPL LPMDLKGEPG PPGKPGPRGP PGPPGFPGKP GTGKPGLHGQ PGPAGPPGFS
RMGKAGPPGL PGKAGPPGQP GLQGEPGIRG DQGLRGPPGP PGLPGPSGIA VPGKPGPQGV
PGPPGFGGEP GPQGEPGPPG DRGLKGDNGV GQPGLPGAPG QGGAPGPPGL PGPAGLGKPG
LDGLPGAPGD KGESGPPGVP GPRGEPGALG PKGPPGVDGV GVPGAAGLPG PQGPAGAKGE
PGTRGPPGLI GPTGYGVPGL PGPKGDRGPA GVPGLLGDRG EPGEDGEPGE QGPQGLGGPP
GLPGSAGLPG RRGPPGPKGD TGPGGPPGVP GIRGDQGPNG LAGKPGPPGE RGLPGAHGPP
GPTGPKGEPG FTGRPGGPGV AGALGQKGDL GLPGQPGLRG PSGIPGLQGP AGPIGPQGLP
GLKGEPGLPG PPGEGKVGEP GVTGPTGPPG VPGSPGLTGP PGPPGPPGPP GAPGAFDETG
IAGLHLPNGG VEGAVLGKGG KPQFGLGELS AHATPAFTAV LTSPFPASGM PVKFDRTLYN
GHSGYNPATG IFTCPVGGVY YFAYHVHVKG TNVWVALYKN NVPATYTYDE YKKGYLDQAS
GGAVLQLRPN DQVWVQMPSD QANGLYSTEY IHSSFSGFLL CPT
//
