ID M3YWJ0_MUSPF Unreviewed; 190 AA.
AC M3YWJ0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=[histone H3]-lysine(4) N-trimethyltransferase {ECO:0000256|ARBA:ARBA00012182};
DE EC=2.1.1.354 {ECO:0000256|ARBA:ARBA00012182};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000015700.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000015700.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) +
CC N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:60260, Rhea:RHEA-COMP:15537, Rhea:RHEA-
CC COMP:15547, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57856,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:61961; EC=2.1.1.354;
CC Evidence={ECO:0000256|ARBA:ARBA00000944};
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DR EMBL; AEYP01042153; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042154; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042155; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042156; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042157; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042158; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042159; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042161; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YWJ0; -.
DR STRING; 9669.ENSMPUP00000015700; -.
DR Ensembl; ENSMPUT00000015941.1; ENSMPUP00000015700.1; ENSMPUG00000015808.1.
DR eggNOG; KOG2084; Eukaryota.
DR GeneTree; ENSGT00940000156766; -.
DR HOGENOM; CLU_127176_0_0_1; -.
DR InParanoid; M3YWJ0; -.
DR OMA; CQKEAWQ; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.220.160; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR12197; HISTONE-LYSINE N-METHYLTRANSFERASE SMYD; 1.
DR PANTHER; PTHR12197:SF288; HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 49..87
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
SQ SEQUENCE 190 AA; 21738 MW; 86BB3CC5EDA42C04 CRC64;
MEPPKVEKFS TANRGNGLRA LAQLRPGELL FRSDPLAYTV CKGSRGVVCD RCLLGKEKLM
RCSQCRVAKY CSAKCQKKAW PDHKRECKCL KNCKPRYPPD SVRLLGRVVF KLMEETPSES
EKLYSFYDLE SNINKLTEDK KEGLRQLVMT FQHFMREEIQ DASQLPPSFD IFEAFAKVPV
NPGPECVIVL
//
