ID M3Z098_MUSPF Unreviewed; 479 AA.
AC M3Z098;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000017009.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000017009.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
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DR EMBL; AEYP01046438; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01046439; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3Z098; -.
DR STRING; 9669.ENSMPUP00000017009; -.
DR Ensembl; ENSMPUT00000017263.1; ENSMPUP00000017009.1; ENSMPUG00000017118.1.
DR eggNOG; KOG1453; Eukaryota.
DR GeneTree; ENSGT00940000154905; -.
DR HOGENOM; CLU_027119_0_0_1; -.
DR InParanoid; M3Z098; -.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0000146; F:microfilament motor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR046987; Myo9.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46184:SF3; UNCONVENTIONAL MYOSIN-IXA; 1.
DR PANTHER; PTHR46184; UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 1..164
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 290..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 257..284
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 299..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 53646 MW; 7BA0992064261CA7 CRC64;
MHGLYTEGIY RKSGSTNKIK ELRQGLDTDA ESVNLDDYNI HVIASVFKQW LRDLPNPLMT
FELYEEFLRA MGLQERKETI RGVYSVIDQL SRTHLNTLER LIFHLVRIAL QEETNRMSAN
ALAIVFAPCI LRCPDTIDPL QSVQDISKTT TCVELIVVEQ MNKYKARLKD ISSLEFAENK
AKTRLSLIRR SMKPVLIAVR FMSITRSSVS GKGRLRRGNY PSPSSPVVVR LPSMSDVPEE
TLTSEATVET DITEQQQAAM QQEERVLTEQ IENLQKEKEE LTFEMLVLEP RASDDETLES
EASIGTADSS ENLNIESEGA ISEKSERSLV LSSLKAAGKS EPSSKLRKQL KRQQDSLDSV
DSSFSALCSS NTASSHGTRK RFQIYSKSPF YRAASAGEAL GVEGPFGQTK SLEDRPQFIS
RGTFNPEKGK QKLKNVKNSP QKTKETPEGT VVTGRRKTVD PDSSSTQQLA LFGNNEFMV
//
