ID M3Z2R6_MUSPF Unreviewed; 287 AA.
AC M3Z2R6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=FOS like 2, AP-1 transcription factor subunit {ECO:0000313|Ensembl:ENSMPUP00000017878.1};
DE SubName: Full=Fos-related antigen 2 isoform X2 {ECO:0000313|RefSeq:XP_044929858.1, ECO:0000313|RefSeq:XP_044929859.1};
GN Name=FOSL2 {ECO:0000313|Ensembl:ENSMPUP00000017878.1,
GN ECO:0000313|RefSeq:XP_044929858.1, ECO:0000313|RefSeq:XP_044929859.1,
GN ECO:0000313|RefSeq:XP_044929860.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000017878.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000017878.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_044929858.1, ECO:0000313|RefSeq:XP_044929859.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_044929858.1,
RC ECO:0000313|RefSeq:XP_044929859.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AEYP01091161; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_044929858.1; XM_045073923.1.
DR RefSeq; XP_044929859.1; XM_045073924.1.
DR RefSeq; XP_044929860.1; XM_045073925.1.
DR STRING; 9669.ENSMPUP00000017878; -.
DR Ensembl; ENSMPUT00000018139.1; ENSMPUP00000017878.1; ENSMPUG00000017989.1.
DR eggNOG; KOG1414; Eukaryota.
DR GeneTree; ENSGT00940000158876; -.
DR HOGENOM; CLU_049742_2_1_1; -.
DR OMA; TVITSMP; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IEA:Ensembl.
DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0061144; P:alveolar secondary septum development; IEA:Ensembl.
DR GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR GO; GO:0042100; P:B cell proliferation; IEA:Ensembl.
DR GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR GO; GO:0035988; P:chondrocyte proliferation; IEA:Ensembl.
DR GO; GO:0032964; P:collagen biosynthetic process; IEA:Ensembl.
DR GO; GO:1904606; P:fat cell apoptotic process; IEA:Ensembl.
DR GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR GO; GO:0060613; P:fat pad development; IEA:Ensembl.
DR GO; GO:0010467; P:gene expression; IEA:Ensembl.
DR GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR GO; GO:0003417; P:growth plate cartilage development; IEA:Ensembl.
DR GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR GO; GO:1901142; P:insulin metabolic process; IEA:Ensembl.
DR GO; GO:0003334; P:keratinocyte development; IEA:Ensembl.
DR GO; GO:0060427; P:lung connective tissue development; IEA:Ensembl.
DR GO; GO:0030225; P:macrophage differentiation; IEA:Ensembl.
DR GO; GO:0070254; P:mucus secretion; IEA:Ensembl.
DR GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR GO; GO:0036446; P:myofibroblast differentiation; IEA:Ensembl.
DR GO; GO:0030223; P:neutrophil differentiation; IEA:Ensembl.
DR GO; GO:0001865; P:NK T cell differentiation; IEA:Ensembl.
DR GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR GO; GO:1904760; P:regulation of myofibroblast differentiation; IEA:Ensembl.
DR GO; GO:1904975; P:response to bleomycin; IEA:Ensembl.
DR GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR GO; GO:0140459; P:response to Gram-positive bacterium; IEA:Ensembl.
DR GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR GO; GO:0035962; P:response to interleukin-13; IEA:Ensembl.
DR GO; GO:0098760; P:response to interleukin-7; IEA:Ensembl.
DR GO; GO:1990823; P:response to leukemia inhibitory factor; IEA:Ensembl.
DR GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR GO; GO:0009410; P:response to xenobiotic stimulus; IEA:Ensembl.
DR GO; GO:0048745; P:smooth muscle tissue development; IEA:Ensembl.
DR GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0048771; P:tissue remodeling; IEA:Ensembl.
DR CDD; cd14721; bZIP_Fos; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR000837; AP-1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR PANTHER; PTHR23351; FOS TRANSCRIPTION FACTOR-RELATED; 1.
DR PANTHER; PTHR23351:SF25; FOS-RELATED ANTIGEN 2; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR PRINTS; PR00042; LEUZIPPRFOS.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715}.
FT DOMAIN 85..148
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 70..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 287 AA; 31008 MW; 864DF41A753AC16E CRC64;
MPGSGSAFIP TINAITTSQD LQWMVQPTVI TSMSNPYPRS HPYSPLPGLA SVPGHMALPR
PGVIKTIGTT VGRRRRDEQL SPEEEEKRRI RRERNKLAAA KCRNRRRELT EKLQAETEEL
EEEKSGLQKE IAELQKEKEK LEFMLVAHGP VCKISPEERR SPPASGLPAL RSGGGGVGAV
VVKQEPLEED SPSSSSAGLD KAQRSVIKPI SIAGGFYGEE PLHTPIVVTS TPAITPGTSN
LVFTYPTVLE QESPASPSES CSKAHRRSSS SGDQSSDSLN SPTLLAL
//
