ID M3Z3G3_MUSPF Unreviewed; 1791 AA.
AC M3Z3G3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Laminin subunit beta 4 {ECO:0000313|Ensembl:ENSMPUP00000018125.1};
GN Name=LAMB4 {ECO:0000313|Ensembl:ENSMPUP00000018125.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000018125.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000018125.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; AEYP01005315; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01005316; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004739573.1; XM_004739516.2.
DR RefSeq; XP_004739574.1; XM_004739517.2.
DR STRING; 9669.ENSMPUP00000018125; -.
DR Ensembl; ENSMPUT00000018391.1; ENSMPUP00000018125.1; ENSMPUG00000018239.1.
DR GeneID; 101674077; -.
DR KEGG; mpuf:101674077; -.
DR CTD; 22798; -.
DR eggNOG; KOG0994; Eukaryota.
DR GeneTree; ENSGT00940000162514; -.
DR HOGENOM; CLU_001560_1_0_1; -.
DR InParanoid; M3Z3G3; -.
DR OMA; RRCSCHP; -.
DR OrthoDB; 90222at2759; -.
DR CDD; cd22301; cc_LAMB4_C; 1.
DR CDD; cd00055; EGF_Lam; 13.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 11.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR013015; Laminin_IV_B.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF435; LAMININ SUBUNIT GAMMA-1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 12.
DR Pfam; PF21199; LAMININ_IV_B; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00180; EGF_Lam; 13.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 13.
DR PROSITE; PS01248; EGF_LAM_1; 3.
DR PROSITE; PS50027; EGF_LAM_2; 12.
DR PROSITE; PS51116; LAMININ_IVB; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1791
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004046054"
FT DOMAIN 24..264
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 265..331
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 332..394
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 395..454
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 455..505
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 506..552
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 545..807
FT /note="Laminin IV type B"
FT /evidence="ECO:0000259|PROSITE:PS51116"
FT DOMAIN 813..860
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 861..906
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 907..954
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1014..1065
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1066..1123
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1124..1171
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1172..1218
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT COILED 1445..1514
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1569..1785
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 297..306
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 362..371
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 425..434
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 477..486
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 489..503
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 506..518
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 508..525
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 527..536
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 813..825
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 815..832
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 834..843
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 861..873
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 863..880
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 882..891
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 926..935
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 938..952
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1038..1047
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1096..1105
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1124..1136
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1126..1143
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1145..1154
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1172..1184
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1174..1191
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1193..1202
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1791 AA; 197361 MW; CF69E72868A14022 CRC64;
MQFQLVFFLH LGLFSYTKAH DERKRGSCHP TTGDLLVGRS AQLTASSTCG LDGAQKYCIL
SYLEGEQKCF ICDSRFPYDP DAPSLSHTIE NVITSFEPET GRKWWQSENG VDHVSIRLDL
EALFQFSHLI LTFKTFRPAA MLVERSADYG HTWKVLKYFA KDCAASFPSI SSGQAQAVGD
LVCDSKYSDI EPSTGGEVVL KVLDPSFEIA NPYSPYIQDL VTLTNLRINF TKLHTLGDTL
FGRRENESLG NYYYALYKMV VQGSCFCNGH ASECGPAQKV RGDVFSPPGM VHSRCVCQHN
TDGPNCERCR DFFHDAPWRP GAGHQDSTCR ACHCNSHADR CHFDMTAYVR SGGRSGGVCE
DCRHNTEGQH CDRCRPLFYR DPLKAMSDPY ACIPCECDPD GTLSGGMCVS QSDPVLGTVA
GQCLCKENVE GAKCDRCKPN HHGLNATDPM GCQPCDCNPF GSLPLSACDV DTGQCLCQTF
ATGPHCEECT AGYWGLEDDL HGCSPCDCDI GGAYSNVCSP KDGQCECRPH VTGRRCTEPA
PGYFFAPLNF YLYEAEEATP LEGRAPLVSA TVLPTCDVYF QQQGSDFTVD KGRIILKSNQ
KQSVPADERS EGSVTFGQVP AFHVVFREPV PGSPVTWTGP GFASVLPGAG LRFVVSNISL
PMDFTIALCY EPQPAADWTV QVLVKPLGGS KHCPRKSPRP RPLSFPLPAA SRIVLLPTTI
CLEPDVQYSI DVHFSRPLEG GPHAQSHILV DSLVLIPQIN SLENFCSKQD LDEYQLHSCV
EIASKTGPQV LPDVCERLIV SMSARLHNGA VACKCHPQGS VGPRCSRLGG QCPCKPHVAG
RCCDRCSPGS YGLGHHGCHP CHCHPQGSKS PICDQITGQC SCQGEVAGRR CDRCLEGYFG
FPSCHPCLCN GFAELCDPET GSCFNCGGFT TGRNCERCID GYYGNPPSGQ SCRPCRCPDV
PSSSQYFAHS CYQHPWSSDV ICNCLQGYAG KQCGECSAGF YGNPRISGAP CQPCACNNNT
DVTDPESCSR LTGECLKCLH NTQGPHCQFC KPGHFGSAIN QTCRRCSCHP SGVNPAKCPP
GRGACLCDPD TGTCPCLPNV MGRACDRCAD GHWNLIPGRG CQPCDCDPRT SHGGHCDQLT
GQCPCKLGYD GKLCSECKED YYRDPLGRCI PCDCNKEGAQ KPTCDRDTGT CHCREGVGGP
RCDRCARGHG REFPACLPCH GCFDPWDHTV SALSKAVQGL MRLAANMRDK REPMRVCEAD
FKGLRENMSE IERILKHPVF SSGEFSTVKD YQDSVREQIM QQSVQMKAVR EFPDLKERIG
RRRNEADLLL EELRREIGLR SHARSASITD SSEDIKRHYQ TSSSAEKKSN ETISIIKNSE
KTRNDLLTIF DTLTSKQNSS LEKLKQIMVP DIQRLKEKVC ADPRDMPCVL AFCDGPSCRS
SPPLSSDALQ QAQEAESAIR NLSDQVQGWK NQLKNVSKLA EISKNSALQL NEKLRNMKNQ
SESEEEKMNL LIKKLKTFLS EENVPPEDIE KVANRVLDVH LPMTSQNLTH ELDKVQKLML
LCEDDGADED RLHNAAKEAQ EVLVKAEDAE KAANVLLNLD KTLNELQQVQ VTQGWVNSTI
TQLTAEIKKI KESTLQAEKK AKHTKNEWDL AKQSSVLEDR LSGLQTKLQR NREQAARVTA
QAASAQRQAG DLKQEFAELR NQYTALQHKT GSVGLTKVTL KKVDQLKGAV EKLATDTEDK
IRRIADLEKK IQELHLSRQE KAEQLKQLED QVVAIKNEIV EQGNKYATCY T
//
