ID M3Z7X5_MUSPF Unreviewed; 187 AA.
AC M3Z7X5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Interferon alpha-1/2 {ECO:0000313|Ensembl:ENSMPUP00000019688.1, ECO:0000313|RefSeq:XP_004761866.1};
GN Name=LOC101674940 {ECO:0000313|RefSeq:XP_004761866.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000019688.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000019688.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004761866.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004761866.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the alpha/beta interferon family.
CC {ECO:0000256|RuleBase:RU000436}.
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DR EMBL; AEYP01053774; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004761866.1; XM_004761809.3.
DR STRING; 9669.ENSMPUP00000019688; -.
DR Ensembl; ENSMPUT00000019968.1; ENSMPUP00000019688.1; ENSMPUG00000019816.1.
DR GeneID; 101674940; -.
DR KEGG; mpuf:101674940; -.
DR eggNOG; ENOG502SQAC; Eukaryota.
DR GeneTree; ENSGT01000000214430; -.
DR HOGENOM; CLU_109427_0_0_1; -.
DR OMA; CVIEERV; -.
DR OrthoDB; 5515844at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0005126; F:cytokine receptor binding; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd00095; IFab; 1.
DR Gene3D; 1.20.1250.10; -; 1.
DR InterPro; IPR009079; 4_helix_cytokine-like_core.
DR InterPro; IPR000471; Interferon_alpha/beta/delta.
DR PANTHER; PTHR11691:SF60; INTERFERON ALPHA-5; 1.
DR PANTHER; PTHR11691; TYPE I INTERFERON; 1.
DR Pfam; PF00143; Interferon; 1.
DR PRINTS; PR00266; INTERFERONAB.
DR SMART; SM00076; IFabd; 1.
DR SUPFAM; SSF47266; 4-helical cytokines; 1.
DR PROSITE; PS00252; INTERFERON_A_B_D; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW ECO:0000256|RuleBase:RU000436}; Cytokine {ECO:0000256|RuleBase:RU000436};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..187
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041198697"
SQ SEQUENCE 187 AA; 21019 MW; 37CC574D3BC1C13F CRC64;
MALPCSFSVA LVVLSCHSLG SLGCDLPQDH GLLHWRALML LRQMRRLSAS SCDNYTNHFG
FPPEAFDNKQ LQKVQALSVI HVTNQKTFHL FCTEASPAPW ITTLLEELCS GISEQLGHLE
ACPLLEAGVG ELPLVNGDSI LRNYFQRISL YLQEKQYSPC AWEMVRAEIM KPLYASTALR
KELRSKK
//
