ID M3ZGX9_XIPMA Unreviewed; 354 AA.
AC M3ZGX9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Protein AMBP {ECO:0000256|ARBA:ARBA00018905};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000001471.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000001471.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000001471.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the calycin
CC superfamily. Lipocalin family. {ECO:0000256|ARBA:ARBA00008238}.
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DR RefSeq; XP_005799718.1; XM_005799661.1.
DR AlphaFoldDB; M3ZGX9; -.
DR STRING; 8083.ENSXMAP00000001471; -.
DR Ensembl; ENSXMAT00000001474.2; ENSXMAP00000001471.1; ENSXMAG00000001473.2.
DR GeneID; 102230973; -.
DR KEGG; xma:102230973; -.
DR eggNOG; KOG4295; Eukaryota.
DR GeneTree; ENSGT00940000160109; -.
DR HOGENOM; CLU_067584_0_0_1; -.
DR InParanoid; M3ZGX9; -.
DR OMA; CPWLKRI; -.
DR OrthoDB; 3558236at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd22596; Kunitz_bikunin_1-like; 1.
DR CDD; cd22597; Kunitz_bikunin_2-like; 1.
DR Gene3D; 2.40.128.20; -; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 2.
DR InterPro; IPR002968; A1-microglobln.
DR InterPro; IPR029856; AMBP.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR46676; PROTEIN AMBP; 1.
DR PANTHER; PTHR46676:SF1; PROTEIN AMBP; 1.
DR Pfam; PF00014; Kunitz_BPTI; 2.
DR Pfam; PF00061; Lipocalin; 1.
DR PRINTS; PR01215; A1MCGLOBULIN.
DR PRINTS; PR00759; BASICPTASE.
DR PRINTS; PR00179; LIPOCALIN.
DR SMART; SM00131; KU; 2.
DR SUPFAM; SSF57362; BPTI-like; 2.
DR SUPFAM; SSF50814; Lipocalins; 1.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 2.
PE 3: Inferred from homology;
KW Chromophore {ECO:0000256|ARBA:ARBA00022991};
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..354
FT /note="Protein AMBP"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004046153"
FT DOMAIN 236..286
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 292..342
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
SQ SEQUENCE 354 AA; 39493 MW; 62032167AD3CC051 CRC64;
MQKSVALVSL LLLGWIGTVQ GLPVLPDPLY STQENFDLSK FLGTWYDVAK ASRSPYMQRY
SGERAIGKLV LQKGSTDEKL KMTRTVLRRG TCLEKTGDYE VTSTPGRFFY HVAKWGADVD
AYVVHTNYNE YAIVIMSKQK SSGDKSISLK LYSRTKSVRP TILEDFKTLA REQGMGDDAI
YVRKDKGDCV PGEMVAEPTP QPEPKRVRRN IVSSLTFDDT EGSGIEAPLF NGTMACNASP
DTGPCFGLLN RYFYNSSSMS CELFQYGGCL GNQNNFVTER ECLQRCRTEA VCRLPMAPQP
CTGQPAIWVF DPSTGVCMPY KQGFCQPNAN KFYTKAECEE YCGVMKDDGL LMSN
//
