ID M3ZKT8_XIPMA Unreviewed; 633 AA.
AC M3ZKT8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Potassium voltage-gated channel subfamily C member 1-like {ECO:0000313|Ensembl:ENSXMAP00000002830.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000002830.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000002830.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000002830.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_014329131.1; XM_014473645.1.
DR AlphaFoldDB; M3ZKT8; -.
DR STRING; 8083.ENSXMAP00000002830; -.
DR Ensembl; ENSXMAT00000002835.2; ENSXMAP00000002830.2; ENSXMAG00000002823.2.
DR GeneID; 102227817; -.
DR KEGG; xma:102227817; -.
DR eggNOG; KOG3713; Eukaryota.
DR GeneTree; ENSGT00940000164903; -.
DR HOGENOM; CLU_011722_4_3_1; -.
DR InParanoid; M3ZKT8; -.
DR OMA; FDGQSNE; -.
DR OrthoDB; 1478695at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18414; BTB_KCNC1_3; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003974; K_chnl_volt-dep_Kv3.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF282; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 3 ISOFORM X1; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01498; SHAWCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 179..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..113
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
SQ SEQUENCE 633 AA; 70592 MW; 6CC1FCCAEA9AD3A9 CRC64;
MTCSASDSEK IVINCGGIRH ETYRSTLKTL PGTRLSWLTE PDAFSNFDYD PKSDEFFFDR
HPATFAFILN YYRTGKLHCP NDVCGPLFEE ELAFWGIDET DVEACCWMNY RQHRDAEEAL
DSFETPEPDV PEDDPALTGG VDGDLKRLCM QEDGRKATWW EVWQPRMWAL FEDPYSSKYA
RYVALASLFF ILLSISTFCL ETHEAFNTIY NKTENVTTGN VTHEEIVYEV VTDGWLTYVE
GVCVIWFTIE VVARVIFCPD KAEFFRSTLN IIDFVAIVPF YLEVALSGLS SKTAKDVLSF
LRVVRFVRIL RIFKLTRHFV GLRVLGHTLR ASTNEFLLLI IFLALGVLIF ATMIYYAERI
GADPKDPTAA AHTDFKNIPI GFWWAVVTMT TLGYGDMYPK TWSGMLVGAL CALAGVLTIA
MPVPVIVNNF GMYYSLAMAK QKLPKKRNKH IPRAPQPGSP NYCKPDALAM ATASPHRLMG
NVIGPGLVES GSMIGTGDCP LAQEEIIEIN RADSKQNGDA AANAAALANE DCPTIDQVLG
DERSPVTGGL GSNTSRERYP HDRACFLLSA GEFQRTTDGN VRKVTGYEKS RSLNNISGMT
GGPLRLTPIT NSTFETFEPS GLRRCHSPIP SIL
//
