ID M3ZWL6_XIPMA Unreviewed; 550 AA.
AC M3ZWL6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Sialic acid-binding Ig-like lectin 5 {ECO:0000313|Ensembl:ENSXMAP00000006610.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000006610.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000006610.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000006610.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. SIGLEC (sialic
CC acid binding Ig-like lectin) family. {ECO:0000256|ARBA:ARBA00038361}.
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DR AlphaFoldDB; M3ZWL6; -.
DR Ensembl; ENSXMAT00000006618.2; ENSXMAP00000006610.1; ENSXMAG00000006599.2.
DR eggNOG; ENOG502S41V; Eukaryota.
DR GeneTree; ENSGT01100000263535; -.
DR HOGENOM; CLU_495160_0_0_1; -.
DR InParanoid; M3ZWL6; -.
DR OMA; INVTITW; -.
DR OrthoDB; 5265804at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR12035; SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN; 1.
DR PANTHER; PTHR12035:SF128; SIALIC ACID-BINDING IG-LIKE LECTIN 12 ISOFORM X1-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..550
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004047049"
FT TRANSMEM 431..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 149..331
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 530..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 60585 MW; 14050BC22DD5A8C2 CRC64;
MFLLAWAIMF LSGALVSVEE YCQQGNYCIT LIKEVTGEAG LCVVIPCSFN TDMKFTPIHI
VWYKSKDDNK SCVFNSENNT NTEAGFKGRV SLLEPDVSQR NCSIVINDLT ESDSGYYQLR
VNGNLSGKPD GFSYNNKTKV SVSALKQKPS VMIPSLTEGQ QATLTCTAPG LCSGSPPNIT
WMWRGKGEND SYITGNMTAL NPENLTDVRL RHSSNLTFIP TAGHHNTKLS CKVSFTASIT
VQEETLNVTY ARKPQISGRT SVKEGHDLNL TCSVDSFPPS EIKFSRKLNG NVPQEVNTSY
YITNAIREDA GLYICTAKHL NSTLTEEINV TITWFSGILN TSGCVLKSEL LTCVCISEGF
PLPTINWSMP LDHTEDSVTV SGQAVRSTVK QTVKSHENIS IKCFSSNENG ETEKNLTIQN
LPDESSTTVP WLEILIVALI GGFIFILLSI IAITYYRKKL KKSGNLVETL ETISPDDPQS
CGGQSVNNAQ FEVQHGAMNG AGTLELNRIS NDLTYAAIDL SKLNMRLEKE ENPNKNETEY
AEIQRQTKSC
//
