ID   M4A163_XIPMA            Unreviewed;       696 AA.
AC   M4A163;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Plakophilin-1-like {ECO:0000313|Ensembl:ENSXMAP00000008207.1};
GN   Name=PKP1 {ECO:0000313|Ensembl:ENSXMAP00000008207.1};
OS   Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Xiphophorus.
OX   NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000008207.1, ECO:0000313|Proteomes:UP000002852};
RN   [1] {ECO:0000313|Proteomes:UP000002852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA   Walter R., Schartl M., Warren W.;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX   PubMed=23542700; DOI=10.1038/ng.2604;
RA   Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA   Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA   Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA   Postlethwait J.H., Warren W.C.;
RT   "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT   evolutionary adaptation and several complex traits.";
RL   Nat. Genet. 45:567-572(2013).
RN   [3] {ECO:0000313|Ensembl:ENSXMAP00000008207.1}
RP   IDENTIFICATION.
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000008207.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the beta-catenin family.
CC       {ECO:0000256|ARBA:ARBA00005462}.
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DR   AlphaFoldDB; M4A163; -.
DR   STRING; 8083.ENSXMAP00000008207; -.
DR   Ensembl; ENSXMAT00000008217.2; ENSXMAP00000008207.1; ENSXMAG00000008184.2.
DR   eggNOG; KOG1048; Eukaryota.
DR   GeneTree; ENSGT00940000156735; -.
DR   HOGENOM; CLU_009111_3_1_1; -.
DR   InParanoid; M4A163; -.
DR   OMA; GVKWLCH; -.
DR   OrthoDB; 5473239at2759; -.
DR   Proteomes; UP000002852; Unassembled WGS sequence.
DR   GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR028435; Plakophilin/d_Catenin.
DR   PANTHER; PTHR10372:SF3; PLAKOPHILIN-1; 1.
DR   PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR   Pfam; PF00514; Arm; 2.
DR   SMART; SM00185; ARM; 4.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT   REPEAT          259..301
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          112..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   696 AA;  76369 MW;  4C85314E5E3EAA0C CRC64;
     MMGLRSTADT GSPDTSLVTP SDKDLSSGQQ RVLSQVNTIK RSKSKYKNGT TSPTSPAPQT
     LKTSDFGMFK YRAASTYSHT NSSGSAAFHN KKSRSLTTKS MKGRLVNSNM EQVNTSSWTK
     SPNGLKPSRS DPVLTSASCL APARSMKAKG QINSSQIQVT KESRSIINGP TFTESQTRIF
     RSPSTQSQTD GKLGTIRVSK IEQSPMVNST GYMQDNITLK EAVEYLSSSN ESYQQQGANY
     IQHISYSEDS AKAEVFDLNG IPPLVNMLDS SNPSLQKAAS GALRNLVFKN MDNKIEVQKS
     GGIAKVLNQM KNTKSTETQR QLAGLLWNLS SAEELKNELI STALIALTKN VVVPYSIPKD
     DSECVDPEVF YFATGCLRNL SSGTAQDREK MRTCEKLIEA LVTYISSCEK EGKSDEKPVE
     NCMCTLHNLT YQLWQECPEA SFSTEAPSEG RKSPTVGCFS PRSRKAKDEI FSNPPQVLAE
     DSNKIALASK VEWLYNSKAT DLYVSLLKSS ENNATKEASC GAMQNLTASK EKGSVAVSEH
     LFKQLADNFL LSSLLRSKAT QKTYASLLDN MSRKPTLLSQ MAPKILPELG KVLSDKAWQG
     EAHPDTVATV CNVLHRLLLV DRDISKKTMS ANMIIGLMET SERDPEDSGS LAASKLLHNL
     WTDKFLRSTI KHLKFDKFKF VNPKTIAAAT KSTPDE
//