ID M4AAS7_XIPMA Unreviewed; 610 AA.
AC M4AAS7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Smoothelin-like protein 2 {ECO:0000313|Ensembl:ENSXMAP00000011571.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000011571.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000011571.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000011571.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; M4AAS7; -.
DR Ensembl; ENSXMAT00000011585.2; ENSXMAP00000011571.2; ENSXMAG00000011551.2.
DR eggNOG; KOG4678; Eukaryota.
DR GeneTree; ENSGT00940000154495; -.
DR HOGENOM; CLU_040651_5_0_1; -.
DR InParanoid; M4AAS7; -.
DR OMA; LCISNGP; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR PANTHER; PTHR23167; CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED; 1.
DR PANTHER; PTHR23167:SF37; SMOOTHELIN-LIKE PROTEIN 2; 1.
DR Pfam; PF00307; CH; 1.
DR SMART; SM00033; CH; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 500..607
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 78..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 65405 MW; 465662D99CB47B3D CRC64;
MEEGAVSRAL AGFRATLDAA VREVHVDVSA FKQQVEHRMD ELRASSRPLS DAVARLQEEN
LQLRTRLDAL SRAVGELAGA RGPENGHNEA GPPDWAAPEP GWGGSGHAEA PGLGSDNPGP
APWRLKRHAD TNGMNAKGGR SNCEEAAADQ EKETEAGVAS ESCDEATPLS HLASETLSSP
DQEESGPLTK PHLPLSATTK TNSDAPVSTP SPTAVAKTSK ESQSKPVESA VISDSHEPQP
HLPVTAMTTK PGLEGFLGAK PVYSPASGRK AAADHLFIGG APGAKDPIAQ NPRDQSDSEA
SSHLPIATAT RIPSDVSAAP KSDQTAASRL NPTAQETPAA LKQTDPPVRH DVNEPKHHLP
LSAMTKPNTE SAISAPSQSL SASLDLTVKP GEYPFKRVPV LKTPSPSLKR SVSFPQPAEK
LLPSKSFMKS GLSPKLDPRS NKSGGIEFKP EAMKSQTLPR SNGAQAKRAL FERMNSDPIK
PKDSKPKLKR SQSFGVSSAS GIKQILLEWC RSKTIGYKNI DIQNFSSSWS DGMAFCALVH
SFFPLEFDYN ALNPANRRQN LQTAFTIAEQ QADCLRLIEV DDMLDMGDKP DPMCVFTYVQ
SLYNHLKKFE
//
