ID M4AJL2_XIPMA Unreviewed; 452 AA.
AC M4AJL2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=CUGBP Elav-like family member 3 {ECO:0000313|Ensembl:ENSXMAP00000014656.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000014656.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000014656.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000014656.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CELF/BRUNOL family.
CC {ECO:0000256|ARBA:ARBA00009621}.
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DR RefSeq; XP_005796502.1; XM_005796445.2.
DR Ensembl; ENSXMAT00000014676.2; ENSXMAP00000014656.1; ENSXMAG00000014619.2.
DR Ensembl; ENSXMAT00000033034.1; ENSXMAP00000035816.1; ENSXMAG00000014619.2.
DR eggNOG; KOG0146; Eukaryota.
DR GeneTree; ENSGT00940000154716; -.
DR HOGENOM; CLU_015367_0_1_1; -.
DR OMA; HAYQGTG; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12632; RRM1_CELF3_4_5_6; 1.
DR CDD; cd12635; RRM2_CELF3_4_5_6; 1.
DR CDD; cd12639; RRM3_CELF3_4_5_6; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR034648; CELF3/4/5/6_RRM1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR24012:SF843; CUGBP ELAV-LIKE FAMILY MEMBER 3-RELATED; 1.
DR PANTHER; PTHR24012; RNA BINDING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 7..88
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 94..174
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 367..445
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 452 AA; 49207 MW; 366EE4C66CB6AF84 CRC64;
MKEPDAIKLF IGQIPRNLEE KDLKPIFEQF GKIYELTVIK DKYTGMHKGC AFLTYCARES
ALKAQNALHE QKTLPGMNRP IQVKPADSES RGDRKLFVGM LGKQQTDTDV RKMFEPFGSI
EECTVLRGPD GTSKGCAFVK FQSNAEAQAA INALHGSRTL PGASSSLVVK FADSEKERGL
RRMQQVASQL GVISPMTLHL GAYNAYTQAL MQQQALVAQS AYLSPVATVA AVQMQQLAAL
NPSSIIATPI ASITPSSGTS TPPSIAATPV PALPPPIAVN SYPSVAAPPN GQSATETLYT
NGVHAYQAQS PVLDPLQQAY TGMQHYTATY PAAYSLVGQP FPHQPTLVAQ QPQQPQQLQQ
REGPEGCNIF IYHLPQEFTD SEILQMFLPF GNVISAKVFV DRATNQSKCF GFVSFDNPSS
AQTAIQAMNG FQIGMKRLKV QLKRPKDANR PY
//
