ID M4AK92_XIPMA Unreviewed; 325 AA.
AC M4AK92;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Abhydrolase domain containing 12B {ECO:0000313|Ensembl:ENSXMAP00000014886.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000014886.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000014886.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000014886.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005799322.1; XM_005799265.2.
DR AlphaFoldDB; M4AK92; -.
DR Ensembl; ENSXMAT00000014906.2; ENSXMAP00000014886.2; ENSXMAG00000014855.2.
DR GeneID; 102235031; -.
DR KEGG; xma:102235031; -.
DR CTD; 145447; -.
DR eggNOG; KOG1552; Eukaryota.
DR GeneTree; ENSGT00940000165086; -.
DR HOGENOM; CLU_029375_1_1_1; -.
DR OrthoDB; 47056at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR022742; Hydrolase_4.
DR PANTHER; PTHR12277; ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12277:SF69; PROTEIN ABHD12B; 1.
DR Pfam; PF12146; Hydrolase_4; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..211
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
SQ SEQUENCE 325 AA; 36232 MW; 4B88F632134352DB CRC64;
MKKVLSFLLT AYVSVPVLLY LFPWILSYAI FSHLLRLPYS VDLRRPQDVL NHTCNFYLSP
EEGVSVGVWH TLPASQWEAA AGRNLDWYQE ALGDGRPVII YLHGNVGTRA ISHRVELVKI
LSAAGYHVLS LDYRGFGDSS GEPSEAGLTN DALYLHQWAK ARSRGIICLW GHSLGSGVAT
NAAVKIQEQG SAVDALILEA PYTRIGEVVA NNRLAKLYMF LPGFESLLWN ILERINISFS
NDKNLQTLSS PLLILHAEDD KVVPFHMGQK LYQISLRAQR ESETGDRVQM ISYGANLGLS
HSRICSAPDL AGVVQKFLQN LERER
//
