ID M4AKG6_XIPMA Unreviewed; 360 AA.
AC M4AKG6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Programmed cell death 2 {ECO:0000313|Ensembl:ENSXMAP00000014960.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000014960.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000014960.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000014960.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005804267.1; XM_005804210.2.
DR AlphaFoldDB; M4AKG6; -.
DR STRING; 8083.ENSXMAP00000014960; -.
DR Ensembl; ENSXMAT00000014980.2; ENSXMAP00000014960.2; ENSXMAG00000014929.2.
DR GeneID; 102223645; -.
DR KEGG; xma:102223645; -.
DR CTD; 5134; -.
DR eggNOG; KOG2061; Eukaryota.
DR GeneTree; ENSGT00940000156603; -.
DR HOGENOM; CLU_034893_2_0_1; -.
DR InParanoid; M4AKG6; -.
DR OMA; HQVIRYS; -.
DR OrthoDB; 5397827at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR GO; GO:0060218; P:hematopoietic stem cell differentiation; IEA:Ensembl.
DR GO; GO:0007088; P:regulation of mitotic nuclear division; IEA:Ensembl.
DR Gene3D; 6.10.140.2220; -; 1.
DR InterPro; IPR007320; PDCD2_C.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR12298; PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED; 1.
DR PANTHER; PTHR12298:SF4; PROGRAMMED CELL DEATH PROTEIN 2; 1.
DR Pfam; PF04194; PDCD2_C; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 138..175
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 195..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 360 AA; 40168 MW; 1C5A8FD3C5B3E305 CRC64;
MSSPEVVLGF LEEAEPWRLQ SPQFPSKVGG KPAWLSQTGL PLQSDLECEK CGLPMVFLLQ
VYAPISGQDR SFHRTLFLFC CKTPECYSHN DSRCLKVFRS QLPRKNEFYS YDPPPDDEPQ
TVSKEDNNIL SLSGVKLCWV CGCPGNKACS RCHTVTYCGK HHQTVHWKHS HKKECLSAAL
PSASASPFLF PESELVTEPE EGGEEGDDAQ RGGGGEEEQK STEGPSLSDT LAEADLEEMA
LHETEDNKVF QRFKKKIASE PHQVIRYSRG GRPLWVSSSH VPAEEEIPPC TCGANRTFEF
QVMPQLLNNL CVDSTGASID WGTVTVYTCS ASCNHGDQYR SEFVWKQDVS ADQLTQHRNT
//
