GenomeNet

Database: UniProt
Entry: M4AL14_XIPMA
LinkDB: M4AL14_XIPMA
Original site: M4AL14_XIPMA 
ID   M4AL14_XIPMA            Unreviewed;      2702 AA.
AC   M4AL14;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 2.
DT   10-FEB-2021, entry version 39.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSXMAP00000015158};
OS   Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Xiphophorus.
OX   NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000015158, ECO:0000313|Proteomes:UP000002852};
RN   [1] {ECO:0000313|Ensembl:ENSXMAP00000015158, ECO:0000313|Proteomes:UP000002852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000015158,
RC   ECO:0000313|Proteomes:UP000002852};
RA   Walter R., Schartl M., Warren W.;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSXMAP00000015158, ECO:0000313|Proteomes:UP000002852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000015158,
RC   ECO:0000313|Proteomes:UP000002852};
RX   PubMed=23542700; DOI=10.1038/ng.2604;
RA   Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA   Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA   Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA   Postlethwait J.H., Warren W.C.;
RT   "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT   evolutionary adaptation and several complex traits.";
RL   Nat. Genet. 45:567-572(2013).
RN   [3] {ECO:0000313|Ensembl:ENSXMAP00000015158}
RP   IDENTIFICATION.
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000015158};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
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DR   STRING; 8083.ENSXMAP00000015158; -.
DR   Ensembl; ENSXMAT00000015178; ENSXMAP00000015158; ENSXMAG00000015125.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   GeneTree; ENSGT00730000111187; -.
DR   HOGENOM; CLU_236004_0_0_1; -.
DR   InParanoid; M4AL14; -.
DR   Proteomes; UP000002852; Unassembled WGS sequence.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 1.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT   DOMAIN          1..304
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1773..1912
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2010..2150
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2621..2665
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          123..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          228..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          387..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          448..472
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          559..587
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1420..1456
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1530..1591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1612..1642
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2442..2463
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2529..2637
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2656..2702
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          20..82
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          169..196
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          692..751
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          816..836
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          865..941
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          946..966
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1012..1039
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1051..1071
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1093..1127
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1156..1190
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1493..1527
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1671..1691
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1699..1754
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1776..1824
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1895..1943
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1986..2143
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2151..2255
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2263..2388
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        127..146
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        256..279
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1434..1456
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1560..1574
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1576..1591
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1622..1640
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2544..2567
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2568..2584
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2589..2605
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2619..2634
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2674..2702
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2702 AA;  309552 MW;  631728B8C96F99C0 CRC64;
     MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKERTQKQFQ LDSLEAALQK QKQKVDSERT
     EISALKRENQ SMIESCDALE KTRQKVVHDL GVKEQQVSYL EGQLNSCRKT IDRLEQELKK
     YKTELDRSQP AGSSLLSTSS SDLQTFSTPQ KTFATPAPVA AHRQPDSKLD ELQEKYNHEV
     EERRKLESEL KMLQVKLLNQ SSVSHKDIAA RQAGSSIFPW QQQDQVHSLR GQDAMETPLK
     RRGASLWDTH EETPIKPNQR MSSSRTVQSP SGSTQQTEQL KSLNQELRGR VSELERNLAA
     QEKEIRNQTS KLQELQTHLN QTRKELAERD RELAKAGHEL SQAADRHQQL EAKCSLVEQK
     LKQVSEEMSC QRHNAESCRR ALEQKLKDQE RNSQKELAQL QSSHQALDQQ LNQTRTKLTQ
     EIQQAKKDHN VLQADMEKTR LQKSQMEREM EEQKQKLLRS EQGLQATQTK EQDLRKKMEE
     LQKEKNGVTI QLDRCSRSLT QLEEEKRISE QSLKRTQGLL EDLKAKSEGQ AEELKRLQSK
     FEQQTQTAAR ELEHVKKTLS DAEARNDKSQ NELQKQKQES EKLSNKLTVI EQESEELKSN
     LRQSRDECQA VKQEHQALLE WKKNKENLIN QTEAAQQELT DKIITLEGKA SRMHEANNEL
     QDKISSTEAD KASLSAHIDA LKGELLMRST ELEEKEHQYQ QLQLHVSEAA QKHGKDLENA
     GKQLAQLQGQ VKELESRLQR EASRAELAEK TNCELQEEHQ AACDLLRSKD QLLELGRAEV
     SQLKDSLAQS AAQQEAQSDS FVKQKAVLLK RCEESISAQA EETERVKLQA EEVQQELLLS
     RHKITSMEQI LKVQEQLGAE LQKQIKTTSD KEEELTKTCE EKSEELKRLE EELKDQRSLT
     EETEQQIRAA EARIHSVENQ KAELENRLQE MKTEAEILQF SHTERMNALQ EQIVCLEKQV
     AANQEEAEEV PVLKNKLDVV NQSLAHLNKS LEASEKSLSC ANEIKADLEV TLSEKVKLIT
     ALEDQINNLT EKLRKESESH SSEVEDFINK ERSLKEQLEA TRKSVAAAKE ESSSRRENIR
     EMKMTLSAAS RGLEERDNTI KSLKEKLNKA EAEQAKASEL LKEKTVAMSK IKVQLEMLQM
     DLEDNELAMT SVGSQAEELK GTIASLEAML EESKAQVSVL ETRLDEVQYQ NSLLETKYVT
     AKDELLERSC EITRLEEDAV RRQQLEENVS ALEAKLSQIT EENSKAETEL RQIIQEKESH
     LEQVNEERNS LQATLTQSVD EQKRAESEIT QVKAVKAELE ERMSNLSKEI QQLHADVREL
     SEQKQEAEGT IDQMAAETQQ TESALRRISE EKAQLDVALS SVSEEKVELQ ERISTLTSEN
     GELVCKVKQV EEEKLQLESK FSQISEENVK QQSDMNRLTA EKQQLQSSAE RLQEEMASLR
     EESERVQSSL LSAEEERQML REQLNTRDET NHTESRARNQ QFEAEQTALH QKLSILQTEL
     AVLQQQYDLL LQQVDQQQRI IQQLTESQKY QNPTGNIPRL EPKDAEDGAE AAEQTKPNPE
     LGANVGTSAE SDPLNEQEEA SEKSPDQAAS EAELIVREDA SDQEMINEEE AHKHDAQEIQ
     LRQQVSEENC SSSGDLENEK YDASSFQHEI RGMKFSGDES WPVKDVDTEM ISEQQSELKT
     LRSEFDLLTS ELQLRAELTS ELEVQVQKLE EKVQAAEEQL STALEEKKSL SDQVTQLLEE
     RESLSLQLET SKCQLTDFME MLEGLEMAKG GLDEKFLQQE SELKRVRSEK ANLEQHILGM
     ESELESMQAE TSRLTEELEI QRKTCSGREQ QIETLLTETT QLRAELVSCS EDRDELSQSL
     GQWRDKVHGL EKTNLETRNL ISILEEDIRV GRKEYEGLQS GMERVKAERE QFLQQVVVLE
     EAISKHNREK EGLLNHLHEM EEDHTSTNQN TESMAGKIQA LEGEVCRLSQ SLESSLLEKG
     EIASRLNSTQ DEVRQMRTGI EKLQVRIESD ERKKKKMGEL LKAAQRKSDS LQDRIDALER
     EKDEFEQNLE EAVLQAEVAK AELEEERTKV EEEKKELNEK LTELSAALDT LTSQKAHLER
     ELDMKNVEIE ELKAAKDKLE QGLEKAEVDR REEDRQRQRL EELEKWTREE AERQSVRVGD
     LQGQLTELER ENNDLRATFE SLGEEIKDLK TLAQAKEEEI LALEKDKENK AESISLIVAE
     KKRLEERNEQ LEKERDDLQS ALVSVNQEKA KADQEKTELD EGRVKLQSKI SLVETEKQNL
     QQTVSLLEQE KLRSEAETEE LQSSLLMMEE EKNNLSSALS LLEEEKQQAT EEKERLTQEH
     EVLQKTVASM EEELETHKRS MTQLSEQVSE LTSSLARLTK ERDSALSKMN LWMKTCKQLE
     QEKQNILNSS GRSSEEFQAE AAQLRAQAEV RKKEVQELKT ALEKKTTEAE ERRQELKQKE
     EEVKERAAAL EGVRAEKERE LEEIRKELDE VNALLEEKST EADESIEKYC SLLVKVHKLE
     ESNDALKTRL EHLTASQPVN EAKVPPETRR RSVRKSSSKH QEEKMSENTE NLVPTTTPSS
     PQGGSPGKRG HKEISDRDSA QEALHNLTKK LKANTATPRG RGEQDDEEFR PEGLPDLVQK
     GFADIPLGEA SPYIIRRTTG RRCSPRLAAR QTKPDIKVSS SSSSPTQRCF PLSQSDLSVL
     IR
//
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