ID M4AL14_XIPMA Unreviewed; 2702 AA.
AC M4AL14;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 10-FEB-2021, entry version 39.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSXMAP00000015158};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000015158, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Ensembl:ENSXMAP00000015158, ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000015158,
RC ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSXMAP00000015158, ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000015158,
RC ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000015158}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000015158};
RG Ensembl;
RL Submitted (MAR-2013) to UniProtKB.
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DR STRING; 8083.ENSXMAP00000015158; -.
DR Ensembl; ENSXMAT00000015178; ENSXMAP00000015158; ENSXMAG00000015125.
DR eggNOG; ENOG502QVMD; Eukaryota.
DR GeneTree; ENSGT00730000111187; -.
DR HOGENOM; CLU_236004_0_0_1; -.
DR InParanoid; M4AL14; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 1.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 1..304
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1773..1912
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2010..2150
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2621..2665
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 123..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1420..1456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1530..1591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1612..1642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2442..2463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2529..2637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2656..2702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 20..82
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 169..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 692..751
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 816..836
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 865..941
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 946..966
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1012..1039
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1051..1071
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1093..1127
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1156..1190
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1493..1527
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1671..1691
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1699..1754
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1776..1824
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1895..1943
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1986..2143
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2151..2255
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2263..2388
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 127..146
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..279
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1434..1456
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1560..1574
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1576..1591
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1622..1640
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2544..2567
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2568..2584
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2589..2605
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2619..2634
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2674..2702
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2702 AA; 309552 MW; 631728B8C96F99C0 CRC64;
MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKERTQKQFQ LDSLEAALQK QKQKVDSERT
EISALKRENQ SMIESCDALE KTRQKVVHDL GVKEQQVSYL EGQLNSCRKT IDRLEQELKK
YKTELDRSQP AGSSLLSTSS SDLQTFSTPQ KTFATPAPVA AHRQPDSKLD ELQEKYNHEV
EERRKLESEL KMLQVKLLNQ SSVSHKDIAA RQAGSSIFPW QQQDQVHSLR GQDAMETPLK
RRGASLWDTH EETPIKPNQR MSSSRTVQSP SGSTQQTEQL KSLNQELRGR VSELERNLAA
QEKEIRNQTS KLQELQTHLN QTRKELAERD RELAKAGHEL SQAADRHQQL EAKCSLVEQK
LKQVSEEMSC QRHNAESCRR ALEQKLKDQE RNSQKELAQL QSSHQALDQQ LNQTRTKLTQ
EIQQAKKDHN VLQADMEKTR LQKSQMEREM EEQKQKLLRS EQGLQATQTK EQDLRKKMEE
LQKEKNGVTI QLDRCSRSLT QLEEEKRISE QSLKRTQGLL EDLKAKSEGQ AEELKRLQSK
FEQQTQTAAR ELEHVKKTLS DAEARNDKSQ NELQKQKQES EKLSNKLTVI EQESEELKSN
LRQSRDECQA VKQEHQALLE WKKNKENLIN QTEAAQQELT DKIITLEGKA SRMHEANNEL
QDKISSTEAD KASLSAHIDA LKGELLMRST ELEEKEHQYQ QLQLHVSEAA QKHGKDLENA
GKQLAQLQGQ VKELESRLQR EASRAELAEK TNCELQEEHQ AACDLLRSKD QLLELGRAEV
SQLKDSLAQS AAQQEAQSDS FVKQKAVLLK RCEESISAQA EETERVKLQA EEVQQELLLS
RHKITSMEQI LKVQEQLGAE LQKQIKTTSD KEEELTKTCE EKSEELKRLE EELKDQRSLT
EETEQQIRAA EARIHSVENQ KAELENRLQE MKTEAEILQF SHTERMNALQ EQIVCLEKQV
AANQEEAEEV PVLKNKLDVV NQSLAHLNKS LEASEKSLSC ANEIKADLEV TLSEKVKLIT
ALEDQINNLT EKLRKESESH SSEVEDFINK ERSLKEQLEA TRKSVAAAKE ESSSRRENIR
EMKMTLSAAS RGLEERDNTI KSLKEKLNKA EAEQAKASEL LKEKTVAMSK IKVQLEMLQM
DLEDNELAMT SVGSQAEELK GTIASLEAML EESKAQVSVL ETRLDEVQYQ NSLLETKYVT
AKDELLERSC EITRLEEDAV RRQQLEENVS ALEAKLSQIT EENSKAETEL RQIIQEKESH
LEQVNEERNS LQATLTQSVD EQKRAESEIT QVKAVKAELE ERMSNLSKEI QQLHADVREL
SEQKQEAEGT IDQMAAETQQ TESALRRISE EKAQLDVALS SVSEEKVELQ ERISTLTSEN
GELVCKVKQV EEEKLQLESK FSQISEENVK QQSDMNRLTA EKQQLQSSAE RLQEEMASLR
EESERVQSSL LSAEEERQML REQLNTRDET NHTESRARNQ QFEAEQTALH QKLSILQTEL
AVLQQQYDLL LQQVDQQQRI IQQLTESQKY QNPTGNIPRL EPKDAEDGAE AAEQTKPNPE
LGANVGTSAE SDPLNEQEEA SEKSPDQAAS EAELIVREDA SDQEMINEEE AHKHDAQEIQ
LRQQVSEENC SSSGDLENEK YDASSFQHEI RGMKFSGDES WPVKDVDTEM ISEQQSELKT
LRSEFDLLTS ELQLRAELTS ELEVQVQKLE EKVQAAEEQL STALEEKKSL SDQVTQLLEE
RESLSLQLET SKCQLTDFME MLEGLEMAKG GLDEKFLQQE SELKRVRSEK ANLEQHILGM
ESELESMQAE TSRLTEELEI QRKTCSGREQ QIETLLTETT QLRAELVSCS EDRDELSQSL
GQWRDKVHGL EKTNLETRNL ISILEEDIRV GRKEYEGLQS GMERVKAERE QFLQQVVVLE
EAISKHNREK EGLLNHLHEM EEDHTSTNQN TESMAGKIQA LEGEVCRLSQ SLESSLLEKG
EIASRLNSTQ DEVRQMRTGI EKLQVRIESD ERKKKKMGEL LKAAQRKSDS LQDRIDALER
EKDEFEQNLE EAVLQAEVAK AELEEERTKV EEEKKELNEK LTELSAALDT LTSQKAHLER
ELDMKNVEIE ELKAAKDKLE QGLEKAEVDR REEDRQRQRL EELEKWTREE AERQSVRVGD
LQGQLTELER ENNDLRATFE SLGEEIKDLK TLAQAKEEEI LALEKDKENK AESISLIVAE
KKRLEERNEQ LEKERDDLQS ALVSVNQEKA KADQEKTELD EGRVKLQSKI SLVETEKQNL
QQTVSLLEQE KLRSEAETEE LQSSLLMMEE EKNNLSSALS LLEEEKQQAT EEKERLTQEH
EVLQKTVASM EEELETHKRS MTQLSEQVSE LTSSLARLTK ERDSALSKMN LWMKTCKQLE
QEKQNILNSS GRSSEEFQAE AAQLRAQAEV RKKEVQELKT ALEKKTTEAE ERRQELKQKE
EEVKERAAAL EGVRAEKERE LEEIRKELDE VNALLEEKST EADESIEKYC SLLVKVHKLE
ESNDALKTRL EHLTASQPVN EAKVPPETRR RSVRKSSSKH QEEKMSENTE NLVPTTTPSS
PQGGSPGKRG HKEISDRDSA QEALHNLTKK LKANTATPRG RGEQDDEEFR PEGLPDLVQK
GFADIPLGEA SPYIIRRTTG RRCSPRLAAR QTKPDIKVSS SSSSPTQRCF PLSQSDLSVL
IR
//
