ID M4AM93_XIPMA Unreviewed; 1486 AA.
AC M4AM93;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Transcriptional repressor GATA binding 1 {ECO:0000313|Ensembl:ENSXMAP00000015587.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000015587.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000015587.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000015587.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 8083.ENSXMAP00000015587; -.
DR Ensembl; ENSXMAT00000015610.2; ENSXMAP00000015587.2; ENSXMAG00000015559.2.
DR eggNOG; KOG1601; Eukaryota.
DR GeneTree; ENSGT00940000157893; -.
DR HOGENOM; CLU_007653_0_0_1; -.
DR InParanoid; M4AM93; -.
DR OMA; SVINHND; -.
DR OrthoDB; 2948149at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR InterPro; IPR028440; TRPS1.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR47034; ZINC FINGER TRANSCRIPTION FACTOR TRPS1; 1.
DR PANTHER; PTHR47034:SF1; ZINC FINGER TRANSCRIPTION FACTOR TRPS1; 1.
DR Pfam; PF00320; GATA; 1.
DR PRINTS; PR00619; GATAZNFINGER.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 945..1003
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT DOMAIN 1328..1355
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 643..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 769..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 884..942
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 994..1059
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1227..1299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1405..1486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..43
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..454
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..662
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..796
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1011..1026
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1059
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1227..1242
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1243..1272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1299
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1417..1471
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1472..1486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1486 AA; 161387 MW; 27F0A2066377B1AB CRC64;
MTSKEMVRKK NPPIRSVGGE EEEEEEGRKP TGEEEDEGDE EERVAAEADR INRPSEPESS
ERIRGNEGQD EEDEAESECI SSVGELYINE ERGGRTAGGG ARAKRVLAAQ CERPESQLES
EDGERGAEGG ENDHLTPPLP SAPRVLSRQE GREESTNDTP ALSSSPSPKL QDFKCNVCGY
GYYGNDPADL VKHFRKYHLG LHNRTRQDAA LDTQILALHN MVPQHTNLDL QTGQGARSQT
KELGKTRADG QNQQQRTVMM NGAYDIQVTL GGTLIGIGRK TSDCQGNTKY FRCKFCNFTY
MGSNSSELEQ HFLSSHPNKV KSPPTTPLLA TNSLATHDSQ LKGRSVMLDA GERVAVRAED
DSVVGYFIPV RAGSDSSGWT GEAGRGAIQA CYWCKLCSWS CEWSEGSAKL LEHYEQRHKA
PAGGAISPNS SGIDRERERG GRKDRGEQDH MASKSCKGHF TTSQGDPKSG DSEAVVTSYN
CQLCDFRYSM AHSADVIIVA PLLLHYQHNH SIHRCCIQHC MYCPQGLCQP QKHLGEVSHP
FACRKPTCSK CCSKFPQPTK QQDAIGSKPT AATSPSVTPP NPRGDPSVIS GSTFYPSNPA
HPVVAQGVTH LCDQCAFATT DIDVLLQHYE SCHSIIKLKG APPQVKAEEE TEGEKEGGRG
GAGETEHTCT KCSFVTQVEE ELFRHYRRVH ACCRCRHCDF TAPDSSALLD HFNSAHCQDA
SPSLGSQPTL MTPSLALSAN GCSAPSTLAI KEESKGDLRL LYSLAPPEGR LAEGGREEPS
GVVKSEGVEE KEREREKGWV LGETRGPGER GGEQAHGLLW VPKERMGPER VAERGAGGGS
PSLFPSPLSL SFVSANHEGS QQKRGMASPG MVYLGDTKPF LGDTKLFLGG GRPGGATAGG
GGGGEKPSQI SSQQYPGGGG GGAGAQEGKG GTTKEESQSL LRRRRGSGVF CANCLTTKTS
LWRKNANGGY VCNACGLYQK LHSTPRPLNI IKQNNGEQII RRRTRKRLNP DTLSSENPAP
KQQRITSEER LNGEELDTRS CPSVKSQQPS PRSRSPRSTQ AFLANQTLEI HRRMPPLLLP
SHPTPAMVAE SNGGITDGGL TSKLEVGKGG GSERGSPIEK YMRPSKPSSY SPPGSPIEKY
QYPLLPLPLP LTLSPDLTPE SDWLRFWTKY KMAATSGVPG SISNLSSPSG IGNNAHHLGT
MVTPVQYHQQ SYTVPYCASP YSPLPPPPAP AHYPPPPPHH AQTLSSASPE NDTPLDLAIR
QRDTSNANMY VSNGAERKRK ESPRSETSMG NWKGEKEREE MAEEGKHESS IVLNCAKADA
ATQDDLANRC THCGIYFLDE VMYALHMSCH GDKEPYQCGF CLHVCADRYD FTTHIQRGLH
KTLPPPQQQD HTPDGKSLNV MAAPECRSQT PAPKDGGITS EDEEVMSTDH DGQEKEDTDS
GSIQEVEKEQ ERSKELCGKT SLDDHKSPEI TTVAESTKLD GLTDGN
//
