ID M4AP97_XIPMA Unreviewed; 276 AA.
AC M4AP97;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Cytokine dependent hematopoietic cell linker {ECO:0000313|Ensembl:ENSXMAP00000016292.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000016292.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000016292.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000016292.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; M4AP97; -.
DR STRING; 8083.ENSXMAP00000016292; -.
DR Ensembl; ENSXMAT00000016316.2; ENSXMAP00000016292.2; ENSXMAG00000016271.2.
DR eggNOG; ENOG502S0EU; Eukaryota.
DR GeneTree; ENSGT00940000161846; -.
DR HOGENOM; CLU_780670_0_0_1; -.
DR InParanoid; M4AP97; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR14098:SF18; CYTOKINE-DEPENDENT HEMATOPOIETIC CELL LINKER; 1.
DR PANTHER; PTHR14098; SH2 DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00017; SH2; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 155..266
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 66..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 276 AA; 31447 MW; C5952627FD03D290 CRC64;
MILLFFKFDS ILAGNYITIY LKSSSLTSAE QIYKDSMLCR SSSPHPPSAL DVSNNLAGLA
VHETYRRDRQ MRNTEKADFR SHARSPQSTK DGSGILSHQR HSLDLETHDL ENRSHQHVGM
ESRRHHHEWP QTKEDIDQND FVPMDKPNTY CEEDWYIGHC NRTDAEHALH LVNKDGAYLV
RDCSNNTNSE PLVLVVYHEK KVYNVKIRFI GSLRKYALGT GQRSNDMFDS VAGIIKFHSI
FPITLVSGRN TASSKCPENC VLTCPITKSD VVQLLQ
//
