ID M4ATY2_XIPMA Unreviewed; 119 AA.
AC M4ATY2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Eukaryotic translation initiation factor 4E-binding protein 1-like {ECO:0000313|Ensembl:ENSXMAP00000017927.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000017927.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000017927.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000017927.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eIF4E-binding protein family.
CC {ECO:0000256|ARBA:ARBA00005480}.
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DR RefSeq; XP_005795040.1; XM_005794983.2.
DR AlphaFoldDB; M4ATY2; -.
DR STRING; 8083.ENSXMAP00000017927; -.
DR Ensembl; ENSXMAT00000017953.2; ENSXMAP00000017927.1; ENSXMAG00000017888.2.
DR GeneID; 102237234; -.
DR KEGG; xma:102237234; -.
DR CTD; 1978; -.
DR eggNOG; ENOG502S4SY; Eukaryota.
DR GeneTree; ENSGT00940000159932; -.
DR HOGENOM; CLU_111706_0_0_1; -.
DR InParanoid; M4ATY2; -.
DR OMA; VNDADHM; -.
DR OrthoDB; 2911937at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IEA:InterPro.
DR GO; GO:0045947; P:negative regulation of translational initiation; IEA:InterPro.
DR InterPro; IPR008606; EIF4EBP.
DR PANTHER; PTHR12669; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN; 1.
DR PANTHER; PTHR12669:SF14; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1; 1.
DR Pfam; PF05456; eIF_4EBP; 1.
PE 3: Inferred from homology;
KW Protein synthesis inhibitor {ECO:0000256|ARBA:ARBA00023193};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT REGION 62..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 119 AA; 12829 MW; 25529C83E1FD07F9 CRC64;
MSTDCQKTTA KTIPSTRRVI INNADHMPHD YSTTPGGTLF STTPGGTRII YDRKFLLECR
SSPLTRTPPR GLPPIPGVTS PPSKGPNEKT VNGEVENNNS ISAPETSNAG EDAQFEMDI
//
