ID M4AXH0_XIPMA Unreviewed; 605 AA.
AC M4AXH0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Kelch like family member 14 {ECO:0000313|Ensembl:ENSXMAP00000019165.2};
GN Name=KLHL14 {ECO:0000313|Ensembl:ENSXMAP00000019165.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000019165.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000019165.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000019165.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; M4AXH0; -.
DR STRING; 8083.ENSXMAP00000019165; -.
DR Ensembl; ENSXMAT00000019193.2; ENSXMAP00000019165.2; ENSXMAG00000019119.2.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000159556; -.
DR HOGENOM; CLU_004253_14_3_1; -.
DR InParanoid; M4AXH0; -.
DR OMA; RETRMQH; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR CDD; cd18453; BACK_KLHL14; 1.
DR CDD; cd18243; BTB_POZ_KLHL14_printor; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR047027; KLHL14_BACK.
DR InterPro; IPR030584; KLHL14_BTB_POZ.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF6; KELCH-LIKE PROTEIN 14; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 2.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 2.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 33..128
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 70..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 68023 MW; 314192C5949716EF CRC64;
MSRSGDRTST FDPTHSDTLL HGLNLLWRKQ LFCDVTLTAQ GQQFHCHKAV LASCSQYFRS
LFSSHNVISN EGSKGDQGSS GTPSSSPDDK LVTTSARPIN NLVLQGCSSV GLRLVLEYLY
TANVTLSLDT VEEVLSVSKI LNIPQITKLS VQFLNDQISV QNYKQICKIA ALHGLDETKK
LANKYLVEDV LLLNFEEMCA MLDALPPPVE SELALFQMSV LWLEHDRETR MHYAPDLMKR
LRFALIPAPE LVERVQSVDF MRSDPVCQKL LLDAMNYHLM PFRQHCRQTM ASRIRSNKRM
LLLVGGLPPG PDRLPSNLVQ YYDDDKKTWK ILTIMPYNSA HHCVVEVENF LLLLGGEDQW
NPNGKHSTNF VSRYDPRFNS WIQLPPMQER RASFFACRLD KHLYVIGGRN ETGYLSSVES
YNLETNEWNY VSSLPQPLAA HAGAVHNGKI YISGGVHNGE YVSWLYCYDP VMDVWARKQD
MNTKRAIHVL AGMNDRLYAI GGNHLKGFSH LDVMLVECYD PKADQWNILQ TPILEGRSGP
GCAVLDDSIF LVGGYSWSMG AYKSSTICYS PEKGTWTELE GEVAEPLAGP ACSTVILPAC
LPFNK
//
