ID M4B058_XIPMA Unreviewed; 465 AA.
AC M4B058;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN Name=CHST2 {ECO:0000313|Ensembl:ENSXMAP00000020103.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000020103.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000020103.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000020103.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc
CC subfamily. {ECO:0000256|ARBA:ARBA00005530}.
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DR RefSeq; XP_005798652.1; XM_005798595.2.
DR AlphaFoldDB; M4B058; -.
DR STRING; 8083.ENSXMAP00000020103; -.
DR Ensembl; ENSXMAT00000020131.2; ENSXMAP00000020103.2; ENSXMAG00000020056.2.
DR GeneID; 102238030; -.
DR KEGG; xma:102238030; -.
DR CTD; 100006249; -.
DR eggNOG; ENOG502QTSD; Eukaryota.
DR GeneTree; ENSGT00940000161292; -.
DR HOGENOM; CLU_028381_1_0_1; -.
DR InParanoid; M4B058; -.
DR OMA; KWRREPR; -.
DR OrthoDB; 3031241at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016469; Carbohydrate_sulfotransferase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10704; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR10704:SF3; CARBOHYDRATE SULFOTRANSFERASE 2; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR PIRSF; PIRSF005883; Carbohydrate_sulfotransferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|RuleBase:RU361155};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 264..439
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 465 AA; 53356 MW; D346655F0A64C195 CRC64;
MRGKQYHQPL KLTAPWEKDA GFGRKLKTYR NHTKIIAQPG IVMKVLRRKR IVLFMAYFLL
LVLTMLNLAN YKWTKEPQQC NHQMRSTTYQ SRSDIRFLYR PSLAKKRQLI YVLTTWRSGS
SFFGELFNQN PEVFFLYEPM WHIWQKLYPG DAVSLQGAAR DMLSSLYRCD LSVFQLYNSP
GGKNFTSLGL FGATLNKVVC SYPLCSAYRK EVVGMVDDKV CKKCPPQSLR LLEEECLKYN
TIVIKGVRIL DVNVLAPLME DPSLDLKVIH LVRDPRAVAN SRIKSRHGLI RENLQVVRSR
DPKLRRIPFV DPGHKVNKKD GSDYHSIGAM EVICDRTSRT LRTALNPPGW LKGKYMAVRY
EDLVENPVKT LRSVYRFANL TTNHDIESFA LNMTSGSSSS SKPFIVSSRN ATQAASAWRM
VLSIQQIKQV EDYCHHSMSV LGYERVRTAG EAKDLSKSLL TRSKL
//
