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Database: UniProt
Entry: M4B0C1_XIPMA
LinkDB: M4B0C1_XIPMA
Original site: M4B0C1_XIPMA 
ID   M4B0C1_XIPMA            Unreviewed;       496 AA.
AC   M4B0C1;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   28-MAR-2018, entry version 44.
DE   SubName: Full=Potassium voltage-gated channel subfamily A member 1 {ECO:0000313|Ensembl:ENSXMAP00000020166};
GN   Name=KCNA1 {ECO:0000313|Ensembl:ENSXMAP00000020166};
OS   Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae;
OC   Poeciliinae; Xiphophorus.
OX   NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000020166, ECO:0000313|Proteomes:UP000002852};
RN   [1] {ECO:0000313|Ensembl:ENSXMAP00000020166}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000020166};
RA   Walter R., Schartl M., Warren W.;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSXMAP00000020166}
RP   IDENTIFICATION.
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000020166};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
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DR   EMBL; AGAJ01037009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005813892.1; XM_005813835.2.
DR   STRING; 8083.ENSXMAP00000020166; -.
DR   Ensembl; ENSXMAT00000020194; ENSXMAP00000020166; ENSXMAG00000020119.
DR   GeneID; 102234059; -.
DR   KEGG; xma:102234059; -.
DR   eggNOG; KOG1545; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00760000118846; -.
DR   InParanoid; M4B0C1; -.
DR   OMA; AHYRQAN; -.
DR   OrthoDB; EOG091G10NU; -.
DR   Proteomes; UP000002852; Unassembled WGS sequence.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR   InterPro; IPR004048; K_chnl_volt-dep_Kv1.1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01508; KV11CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01496; SHAKERCHANEL.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002852};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00984201}.
FT   TRANSMEM    168    188       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    218    239       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    327    348       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    388    409       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       36    136       BTB. {ECO:0000259|SMART:SM00225}.
SQ   SEQUENCE   496 AA;  56413 MW;  B366BF42AB60C485 CRC64;
     MTVVSTENMD DTSTLPGHPQ DPYPLDDDHN DHDCCERVVI NISGLRFETQ LKTLAQFPDT
     LLGNPKKRMR YFDPLRNEYF FDRNRPSFDA ILYYYQSGGR LRRPVNVPLD MFSEEIKFYE
     LGAEAMEKFR EDEGFIREEE RPLPEKEFQR QIWLLFEHPE SSGPARGIAI VSVMVILISI
     VIFCLETLPE LKEDPNDRIH QVGNTTMYYK ASVLTDPFFV VETLCIIWFS FELIVRFFAC
     PSKAAFFKNM MNTIDIVAII PYFITLGTEL ADDQGSREGR GGGEQATSLA ILRVIRLVRV
     FRIFKLSRHS KGLQILGQTL KASMRELGLL IFFLFIGVIL FSSAVYFAEA EEKESFFTSI
     PDAFWWAVVS MTTVGYGDMY PVTIGGKIVG SLCAIAGVLT IALPVPVIVS NFNYFYHRET
     EGEEQAQLLN ISNQNLASET NSSRRTSSVV SKSEYMEIDE DLNNSIDNFR EANLRTANCT
     APSQNCVNRG KLLTDV
//
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