ID M4B876_HYAAE Unreviewed; 779 AA.
AC M4B876;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=G-patch domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP802478, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP802478}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP802478};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; JH597957; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4B876; -.
DR STRING; 559515.M4B876; -.
DR EnsemblProtists; HpaT802478; HpaP802478; HpaG802478.
DR VEuPathDB; FungiDB:HpaG802478; -.
DR eggNOG; KOG0154; Eukaryota.
DR HOGENOM; CLU_011731_0_0_1; -.
DR InParanoid; M4B876; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR13948:SF3; FI21118P1; 1.
DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 65..114
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 702..749
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 650..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..665
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..696
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 779 AA; 85262 MW; 615EBAE4FF6CA913 CRC64;
MHLAVSSSAR PHIQQQQHES MSGPPHFDRQ KSVLPPRGQQ NRPYVSAQDH VPSATLLLHG
LARSVTEEMA TGESRGFAYV DFGSVEDATD VIRAFELKPL VLEDREVDVK YSDGFRRGAD
SGRSRDLTAD SRLKKTYYGS QGQEERRQPR PDWICDDCTA PKTAHAKEVL ATTASRADHT
RGYNDSYGGE SRSSRSSLGT SSRDSEITFR RREDRGNSTW SVPPSQVLVV RMLPPDIEEG
EAATNALKKS EGFIVQNTRV EISYARDTLS NRSRYSPYVP QESRAGSSLA VTALEQAQWS
LSQGRGVDGA RNDQVNACCF FLFAKLGDMF VPGVRNKYLI FKVSLLLPHT CAKNCCIVRV
FLTDILSRVA LRPMSVHCWI VLQLKSFLGL KNRRNCGQHR SRQQAAAMCI LFYYDPPTSV
YYNSFTGVYY RCVSPAGSRA AAFQAFVPPL PVDDEAYQEE CTAATAASKP MMSMSLKKDK
KKTSGISFSL KTAAFGATLA SSKLSSTKSS VAASVVTAVN VASGMKRKSA GDIAKWSQRQ
QEAKKQKSKD VDITPVQQQQ QRTEPSAVSI ADHGEATTFA DSSQQRAAVS AVNHAVDSVI
DALTNVPQEA PICLLCRRKF GSLEILRKHE TLSKLHLANL AKVRENKQHI AAQQREHELQ
VEQLAKKQRQ DGNAPSNAPS GTDRQSASTP GSKSAHPEPT LESGIGGKML KMMGWKSGEG
LGKHNTGITA PIEAASGRTD LAGLGCKAPL SASVDLSDVT TDRERRQRLA RARYDADSA
//
