ID   M4BI33_HYAAE            Unreviewed;       963 AA.
AC   M4BI33;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   RecName: Full=MPN domain-containing protein {ECO:0000259|PROSITE:PS50249};
OS   Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS   (Peronospora arabidopsidis).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Hyaloperonospora.
OX   NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP806059, ECO:0000313|Proteomes:UP000011713};
RN   [1] {ECO:0000313|Proteomes:UP000011713}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX   PubMed=21148394; DOI=10.1126/science.1195203;
RA   Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA   Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA   Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA   Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA   Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA   Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA   Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA   Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA   Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA   Tyler B.M.;
RT   "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT   arabidopsidis genome.";
RL   Science 330:1549-1551(2010).
RN   [2] {ECO:0000313|EnsemblProtists:HpaP806059}
RP   IDENTIFICATION.
RC   STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP806059};
RG   EnsemblProtists;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the CNOT10 family.
CC       {ECO:0000256|ARBA:ARBA00010080}.
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DR   EMBL; JH598278; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 559515.M4BI33; -.
DR   EnsemblProtists; HpaT806059; HpaP806059; HpaG806059.
DR   VEuPathDB; FungiDB:HpaG806059; -.
DR   eggNOG; KOG1795; Eukaryota.
DR   eggNOG; KOG2471; Eukaryota.
DR   HOGENOM; CLU_013100_0_0_1; -.
DR   InParanoid; M4BI33; -.
DR   Proteomes; UP000011713; Unassembled WGS sequence.
DR   GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR   CDD; cd08056; MPN_PRP8; 1.
DR   Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR039740; CNOT10.
DR   InterPro; IPR037518; MPN.
DR   InterPro; IPR012984; PROCT.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR12979; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10; 1.
DR   PANTHER; PTHR12979:SF5; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10; 1.
DR   Pfam; PF08084; PROCT; 1.
DR   Pfam; PF13432; TPR_16; 1.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF48452; TPR-like; 3.
DR   PROSITE; PS50249; MPN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011713}.
FT   DOMAIN          1..88
FT                   /note="MPN"
FT                   /evidence="ECO:0000259|PROSITE:PS50249"
SQ   SEQUENCE   963 AA;  107071 MW;  400689EC4E25B589 CRC64;
     MPPQLGTHQS VTIPLHLPDH EYLEGMEALG WIHTQPNELP SLPPQDVTFH SKIMSENTSW
     DGEKSIIITC SFTPGSCSLT AYKLTPAGYE WGRQNKDGGA NPVGFVPTHY EKVQMLLSDR
     FLGFYMVPDE EVWNYNFMGV KHNTGMKYDL KLGNPKEFYY EIHRKTHFMN XXXXXXXLAR
     LKRRTKMRLL MRSSRTYLPN LHVSITSPLY QRAVASVERG VKQKQLLLLR SVPNRLYTNR
     KKRLMSGDVR AKDNKSSLSH RAQQKFNAGK YEEAVDALEK LVDEIDSRQD FKVRHNVALA
     RFAAGLDTPG KMQLALQQIL RAELQENDKK PALATAADVA VNGEDAAVGV DVAAEDSGSF
     SIERETAYLR YNYAAALFMS KQYAQASAVL ETVMRNVDPI DENVAMHASF LYLDVILHSS
     RGCVSTERER AATSKKAQSI MAFLEKPHRF NTVQQPPDHL VQRDVNGNAM ETEIQKKNRW
     DVTEFRFRLH LYRAKSMLLQ SNLKTAKKEV KSALEILQKE IKTYDRGDAA AAPSSSLALE
     SEKTSAAIGH PRLVVQNSTA LFLKANLEYL KKNYKKCIKL LASCTQEAVS ESVLLNNMGC
     IHFQMGQRKA AQSYFARALQ ATTKATKMDA VAIASSCQYE IMYNNGLHLL LQGEFALAFR
     CFHESSRLFF NRPKLWLRLG ECCTAAFAKE QKLAVVAGNT SGLIQGIVGT GSHRRVLLPT
     SLPSAASQDI KLAEMDSNGI GSRTASVDDD DVGGSPTMSL PFGAKCFKNV VLLCNQLLDS
     RNVSGNTNTP VGAADGPKSE PLDTEALDVL RQKALVNLSY VYLSMYEPQL AIASAKDLLA
     LATCSKVNCF LARSYTAEAL CMLSRASEAT DALQSERDLI VMAEDYAREA KIQVSRARAG
     VHVSNATALL LQGRNSEAEE SVTRAVRENP SCRESLELLV YVLLKKGDTK KALRVLKEAQ
     VVQ
//