ID M4BP07_HYAAE Unreviewed; 425 AA.
AC M4BP07;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=AP-3 complex subunit mu {ECO:0000256|ARBA:ARBA00040763};
DE AltName: Full=Adaptor-related protein complex 3 subunit mu {ECO:0000256|ARBA:ARBA00043093};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP808145, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP808145}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP808145};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|ARBA:ARBA00005324, ECO:0000256|PIRNR:PIRNR005992}.
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DR EMBL; JH598476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4BP07; -.
DR STRING; 559515.M4BP07; -.
DR EnsemblProtists; HpaT808145; HpaP808145; HpaG808145.
DR VEuPathDB; FungiDB:HpaG808145; -.
DR eggNOG; KOG2740; Eukaryota.
DR HOGENOM; CLU_026996_6_2_1; -.
DR InParanoid; M4BP07; -.
DR OMA; INVHFTI; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd09252; AP-3_Mu3_Cterm; 1.
DR CDD; cd14837; AP3_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR PANTHER; PTHR10529:SF340; CARMINE, ISOFORM A; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 1.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|PIRNR:PIRNR005992};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Transport {ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 176..424
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 425 AA; 47960 MW; 107D05E5AE4544FD CRC64;
MIQSMFILTT TGEVIIEKHW RGLTSRNVCD FFMEEVNKYR EREDVPPIIT TSKYYLVSTF
RDDLFVLAVV TNEISPLFVI EFLQRVLAVF RDYFGNFDEN SIKDNFSTVY QLLEEMLDNG
YPLTTEPNAL KAMVAPPSTA NRIASMVSGK SRVSNTLPDG AISNIPWRKS GVRYTQNEIY
FDIFEEIDAI IDVSGRMISC EVNGSIQSNS RLSGVPDLTM VFTDPSVIDD CSFHPCVRYS
RYERERVISF VPPDGQFELM QYRVQVNDLV PPLYCQPQIT YNDKGGGTLD LVIGTRGMPT
LNSNARRNLQ VEDVTVQVSF PKSVRTVDVN TESGTCLFDE PSKTVKWNVG KLGKKVLNPS
LRGNIILHQG AAVPDEKPVV LLGFKVPMST VSGLNVETLL ITNEKYKPYK GVRTMTKAGR
FQIRM
//
