ID M4BQ46_HYAAE Unreviewed; 531 AA.
AC M4BQ46;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 13-SEP-2023, entry version 34.
DE RecName: Full=Glycosyl hydrolase family 30 TIM-barrel domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP808535, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP808535}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP808535};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC {ECO:0000256|ARBA:ARBA00005382}.
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DR EMBL; JH598544; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4BQ46; -.
DR STRING; 559515.M4BQ46; -.
DR EnsemblProtists; HpaT808535; HpaP808535; HpaG808535.
DR VEuPathDB; FungiDB:HpaG808535; -.
DR eggNOG; KOG2566; Eukaryota.
DR HOGENOM; CLU_014379_1_0_1; -.
DR InParanoid; M4BQ46; -.
DR OMA; NQIVMQF; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR033452; GH30_C.
DR InterPro; IPR001139; Glyco_hydro_30.
DR InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR Pfam; PF02055; Glyco_hydro_30; 1.
DR Pfam; PF17189; Glyco_hydro_30C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 2..321
FT /note="Glycosyl hydrolase family 30 TIM-barrel"
FT /evidence="ECO:0000259|Pfam:PF02055"
FT DOMAIN 324..387
FT /note="Glycosyl hydrolase family 30 beta sandwich"
FT /evidence="ECO:0000259|Pfam:PF17189"
SQ SEQUENCE 531 AA; 60175 MW; B210EA19F863DEAD CRC64;
MARVPIGSTD FSPRTYTYNE KVDDFAMTNF TIASDKAPLS NKINLIQRAL SMAKLRLFAS
SWAPPLWMTR GQSVVDCKIK GSPGEKYWAA LALYYSKFFD AYKGEGIEFW AMTVQNEPEE
PTIHIPNWET LRMTPEEERD FIKLNLGPLM ARNHPVLKIL ANDDQKSGLL DRSAPFDDPE
SKKYISGVAF HWYKNLDFIL PGAGNYRNLK KFNEAYPDVF MLGSEACEGY MPRFIGTGRG
PSMDDPERTW KRAQNYARDI IENSNNMAAG WVDWNLFLDS KGGPNWAENM VDAPILVAEH
NGTEFYKQPM YYIMGHFSKF VPPGSRRIEL PKSETLSDFH RCAFVTPSNQ IVMQFLNRKE
SEVTISVKEP NLHTFTLKLP AKSMQTIILP ASADTTILPA SKDSTPRAKI SRNVIRAHFR
LGIFCCCISR VSSPTHHVNA QHYFGIGRRA YCKADCLGDG IGELSCDQLI ECPSTPYWVP
TSPPLIQMEA VSPRRLATRP FGHGKRPVDF TATLRLSRDP KSRRTRSINV Q
//
