ID M4BRG3_HYAAE Unreviewed; 2716 AA.
AC M4BRG3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP809003, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP809003}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP809003};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SEC16 family.
CC {ECO:0000256|ARBA:ARBA00005927, ECO:0000256|RuleBase:RU364101}.
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DR EMBL; JH598638; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 559515.M4BRG3; -.
DR EnsemblProtists; HpaT809003; HpaP809003; HpaG809003.
DR VEuPathDB; FungiDB:HpaG809003; -.
DR eggNOG; KOG1913; Eukaryota.
DR HOGENOM; CLU_227659_0_0_1; -.
DR InParanoid; M4BRG3; -.
DR OMA; GGDHRTP; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd09233; ACE1-Sec16-like; 1.
DR Gene3D; 1.25.40.1030; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR PANTHER; PTHR13402; RGPR-RELATED; 1.
DR PANTHER; PTHR13402:SF6; SECRETORY 16, ISOFORM I; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU364101};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU364101}; Membrane {ECO:0000256|RuleBase:RU364101};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU364101};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Transport {ECO:0000256|RuleBase:RU364101}.
FT DOMAIN 1776..1903
FT /note="Sec16 central conserved"
FT /evidence="ECO:0000259|Pfam:PF12932"
FT DOMAIN 1958..2229
FT /note="Ancestral coatomer element 1 Sec16/Sec31"
FT /evidence="ECO:0000259|Pfam:PF12931"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 885..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1176..1213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1358..1378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1438..1457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1687..1722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2290..2553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2598..2653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2682..2716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..824
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1141..1163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1268..1315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1318..1334
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2290..2323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2335..2349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2377..2415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2427..2451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2464..2520
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2622..2642
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2700..2716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2716 AA; 287118 MW; F53571FAA72530F4 CRC64;
MDGGRGFFSA TSSTPNEASR DGDGLRNQRL RVDTRLSQKP AAPQDFFASL GVDSTSRGRT
GSTSSTRSHS SSTSTTSIMR SKSVAGKESA TPTSGWRPPT IGGLGSQRAA PPSPAPSAVS
VSGVNRNVVN AATFASSSSI RGEEGSMTTS VTSGSTITLP SGSDGGAKPS AAPTQLFSMD
DAEELFSDDG WQCDLPPVVL SDPTDETELG STVSAAATNA DDHVTWSDGD DALASSVAKP
VEVRTGLDAV HAGGRTDVTF GSVTDQAAAA STENEFGANS FSSAQVPSSG MKSPYQDART
EVATLPPRAV KSPSSFFMEE PQSTFEITSH SGTQRTSLSG TSQVTSFSET SATYKPYQQD
EQWDDEWGNQ QKESATAELR PVAAGDFSPP HTTAILTATT GHTDLYVTPP VELTSPGGAA
GEFWGDGDED ELFAQDDYVD EDWNEPIEDN PNAHANSASR SSVSHVDSAA PTSPSHDTSY
LLLRQPQPPS SGSAFDVRSL PKHSEQHNQM VGRLTESTRA LTMPYLFESN SATFVEEKST
VAVQSAESSR FVEPKLSLRT ERLQFSSAIA GSTNQDNDLN VFPEAPRSSA RFLHTPTGTG
GPFGRVPSPH GTDQSFFSEE MSGNVARMAV HDSITFASEE KVEKLNSHTE PSVRMESHSG
EHNQLYSEDQ PNEDDDRSRR DNYNRQSDEE ERDSVVSFSG EKSFFLSTGR PSSTYGGSQS
SFASHRMYQS SIASTDHDGS SIASFGVSSA GATFGGSERV SEGGAYSDGA VSESPSMVNS
SNASTAFGTD FPSASEGQFS APGTTIGGSD NASDGGFSDG NVSETTSMCE SVHTNSRFVT
DFSISGGEYA SVGAVEHCSM QGVYASSAPE SDSVAPFGEA APTAAATNFG GDDGPADVDP
FTSSPSIFTS SERASNAPLA TALGDSRFDH QPEVTVLEEN IQSAASLFDA TAGADVPNPF
GSFGPSSAPA VATPIGEHEL PTSDAGDLFG AAVPSSGFQS SFAQPAQNAY GSIQSFDQAY
NKADNEARPD TNTNTNTQTS AVDFVQSPFT SVDTHDRDVS VSSVGTQRFV DQNRLDPFAS
RSLQHGFDNS ATSAESVFSS GGDYGHSSNP DRRASLHFGG DLQTPANAAY SRPARNAASV
AGHFGQQSNA PSTPHSADQS YSDCTTTYSD QALVGAPNYE NQSGLGDGAH TGANTIRTRP
YGQSDGDTAG AESATAYGSE GFRQSDYQSL TAHNARQREV SGFGGGSHAS RLTSQNGYSQ
KPAAVTFASA GQPTPSYGSQ QIGQSRTTGS PTKYSYRSTA GEVGSGSQTA PSHAGRQHNR
CAHNDSDADI GKSADVGELS RPSPHAFFGH LSIGPSSVSD VGDDRAKPLS SGTTQQQPLV
QTRVQESFVR GGSNASSHAE LQHSRLPVDS TAIQASMHPR DANASYESVG DASLSRHASS
SSISHYEGER SFRPEQNLRE ESASAYASID ANSYAGGVLS GTGIEAASLL FESSVSEDSS
KLHIPLSQVS TFNESSMRVV SQFASPHQDL VQQRGRAQPS DREFENVTVV APKYSHPVPA
VEARSRPDVG MTTAMASPVA KDDDKCYQGL ERRCDWGSYS VGGNVSSVAL ASLASQTAPS
MSNQFEHMSY GQTSEQQQDR IRYSAASSSH SSYVGAHAFG DNSAGSYFES RAPDDGTAAS
HTFFQQQQLQ EQQYQSHQQQ QQQQPQLHHV VTGYTNPGSA VQNELQGASY GAASQHEYEN
ATADGSYQHA TRAAPTSAIK TSNEYKDPCV APPSCLASFG FGGNMVTMFP KRKLRLSVAG
SSVYDSPRGA LIPSKLDNGG DSKRCIGPVH VYRMNQLHPN NVEFEQMDIF PGPLTEDVSV
EEILRYLDDR LKRSEALPTT VKAEDENDRV LLGVLRVLIK CNGKLRSEPG NLNPGAPDTP
EAQLITLLSE SSKRRNGFNP LTFPEPQEVQ SKTNTNVLRE LLLAGDRKGA VSSAMTANMW
PEAILIASFV DKEMYKRVLR IYLDGHYTAG DPCRALFLTF ADQQENSVQE PKPLLQTSVH
QPTESLILSN WVSHAQVLLS NRTADTNKIL TELGDRLWSE ANTVSAAHIC YLLASIQLGA
PTPSSKMALL GGDHRTPAEA RFYVSPGTVQ CTEIYEWAQK QSKNASANLM VPFQGYKIIY
TMLLADHGKL DTAFKYVTSM LTVIKAMTAT MKPGTSVYLE GMKNQLVILD DRLRQHLGQD
RVASMAASIS RGGGSKQTGK WGLGSALSMM GKIVNRVVEG PESDTASSAV PSTSTSGGVF
VNEASLPAAS YPNTPSVKAM TSSPTPTCPQ QSSQPNRPQG SFGSTVPAGM YGHATPPVSQ
NSAPGFSNGY QRAHTEPPAV EPSSRSGVAP SAHAVTNGHL APTSGPFNGN ERQQQSASEP
IVNTDNHGNS RRFSNKGPKL QKHGVAPRMY SQQSMEFSEN TYSTRSSNDF GAADSPCAPL
QQQPPFVLKS QQGSHAHPAL QNRSALNTSD DIRSSSQPKT HHADLAPVSP TDTTSMSGPA
SGDKGKAGPM LDVAKKPGRF ETPPHSNSGK GSGWLSGLSS FIATKINPEA KIAKLGEQME
AYFDEDAKRW VFPGETAPEE ATMPSAPPTG PLLGSAPGSS AAGMPPTGTA SAPGSISSGP
TPNDPLAALM APPPPRVLMK KDPLAAMMAP PARPGIYGMH RSASMTQRKT ARPQFAVFKP
TAPPQTSPAD NVSIMS
//
