ID M4BUE8_HYAAE Unreviewed; 573 AA.
AC M4BUE8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:HpaP810136};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP810136, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP810136}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP810136};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABWE02000678; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4BUE8; -.
DR STRING; 559515.M4BUE8; -.
DR EnsemblProtists; HpaT810136; HpaP810136; HpaG810136.
DR VEuPathDB; FungiDB:HpaG810136; -.
DR eggNOG; ENOG502QPYM; Eukaryota.
DR HOGENOM; CLU_018563_2_0_1; -.
DR InParanoid; M4BUE8; -.
DR OMA; GIDDHWF; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17484; MFS_FBT; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR004324; FBT.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00788; fbt; 1.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF6; FOLATE-BIOPTERIN TRANSPORTER 2-RELATED; 1.
DR Pfam; PF03092; BT1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 110..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 536..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 62798 MW; 3218F7A936021EEC CRC64;
MAGSIFYPQL SIMALETVAS PLSERLPRLG LDNVHLEVVE VSTTSHPEPE LDPLDKCKGV
TSLNSLSNST DLAAKTRGSD ENNRDTNGLS KAKRFVIWVQ HLRRTFGTSF LIMINIVYIA
QGFSSFTVLA INFFFKENLR LEPTQSQLLQ MLMKVPWRVK PIYGILSDSL PLFGYHRKSY
MVLCSILGIA AALALAHPDL VTTPTVAVLV LMLQSLSSAV IDVVVDARVV EFSRRDPKNG
ANDLQSLSWI SGSLGGMLGA FLSGPATDKL GARGVFGVSA LGPLTTLMFS MYMEESKSTL
SKRQFVSSAT KQLRQLRVAI CTPVIWKCAL WVFISHALSP AYTQVLFYFS TDVLQFTPEF
MGTVSAIGFI FLMVATILYN SFFTNVSFRR IFLVSQLCLA LVSLVDVILV TRTNLQLGIP
DKAFVLGDHV VADVIGRLKT MPIVVLCAKL CPRGIEGTLF ALLMSISNVS YSVSECWGAL
LCDWVGISKD EYEMLGIAIV VRSAFKVVPI FFLFLIPSSD PQDIIEKLDL GTSSRTALED
DDEQSGTIQE DHPAESCSPS EKIVLEGTAV AVL
//
