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Database: UniProt
Entry: M4ELJ7_BRARP
LinkDB: M4ELJ7_BRARP
Original site: M4ELJ7_BRARP 
ID   M4ELJ7_BRARP            Unreviewed;       379 AA.
AC   M4ELJ7;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   16-OCT-2019, entry version 31.
DE   RecName: Full=Arogenate dehydratase {ECO:0000256|RuleBase:RU363004};
DE            EC=4.2.1.91 {ECO:0000256|RuleBase:RU363004};
OS   Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica
OS   pekinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae;
OC   Brassica.
OX   NCBI_TaxID=51351 {ECO:0000313|EnsemblPlants:Bra029665.1-P, ECO:0000313|Proteomes:UP000011750};
RN   [1] {ECO:0000313|EnsemblPlants:Bra029665.1-P, ECO:0000313|Proteomes:UP000011750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chiifu-401-42 {ECO:0000313|EnsemblPlants:Bra029665.1-P,
RC   ECO:0000313|Proteomes:UP000011750};
RX   PubMed=21873998; DOI=10.1038/ng.919;
RG   Brassica rapa Genome Sequencing Project Consortium;
RA   Wang X., Wang H., Wang J., Sun R., Wu J., Liu S., Bai Y., Mun J.H.,
RA   Bancroft I., Cheng F., Huang S., Li X., Hua W., Wang J., Wang X.,
RA   Freeling M., Pires J.C., Paterson A.H., Chalhoub B., Wang B.,
RA   Hayward A., Sharpe A.G., Park B.S., Weisshaar B., Liu B., Li B.,
RA   Liu B., Tong C., Song C., Duran C., Peng C., Geng C., Koh C., Lin C.,
RA   Edwards D., Mu D., Shen D., Soumpourou E., Li F., Fraser F.,
RA   Conant G., Lassalle G., King G.J., Bonnema G., Tang H., Wang H.,
RA   Belcram H., Zhou H., Hirakawa H., Abe H., Guo H., Wang H., Jin H.,
RA   Parkin I.A., Batley J., Kim J.S., Just J., Li J., Xu J., Deng J.,
RA   Kim J.A., Li J., Yu J., Meng J., Wang J., Min J., Poulain J., Wang J.,
RA   Hatakeyama K., Wu K., Wang L., Fang L., Trick M., Links M.G., Zhao M.,
RA   Jin M., Ramchiary N., Drou N., Berkman P.J., Cai Q., Huang Q., Li R.,
RA   Tabata S., Cheng S., Zhang S., Zhang S., Huang S., Sato S., Sun S.,
RA   Kwon S.J., Choi S.R., Lee T.H., Fan W., Zhao X., Tan X., Xu X.,
RA   Wang Y., Qiu Y., Yin Y., Li Y., Du Y., Liao Y., Lim Y., Narusaka Y.,
RA   Wang Y., Wang Z., Li Z., Wang Z., Xiong Z., Zhang Z.;
RT   "The genome of the mesopolyploid crop species Brassica rapa.";
RL   Nat. Genet. 43:1035-1039(2011).
RN   [2] {ECO:0000313|EnsemblPlants:Bra029665.1-P}
RP   IDENTIFICATION.
RC   STRAIN=cv. Chiifu-401-42 {ECO:0000313|EnsemblPlants:Bra029665.1-P};
RG   EnsemblPlants;
RL   Submitted (AUG-2019) to UniProtKB.
CC   -!- FUNCTION: Converts the prephenate produced from the shikimate-
CC       chorismate pathway into phenylalanine.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + L-arogenate = CO2 + H2O + L-phenylalanine;
CC         Xref=Rhea:RHEA:12536, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:58095, ChEBI:CHEBI:58180;
CC         EC=4.2.1.91; Evidence={ECO:0000256|RuleBase:RU363004};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-
CC       phenylalanine from L-arogenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC       {ECO:0000256|RuleBase:RU363004}.
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DR   STRING; 3711.Bra029665.1-P; -.
DR   EnsemblPlants; Bra029665.1; Bra029665.1-P; Bra029665.
DR   Gramene; Bra029665.1; Bra029665.1-P; Bra029665.
DR   InParanoid; M4ELJ7; -.
DR   OMA; HTRFVIL; -.
DR   UniPathway; UPA00121; UER00344.
DR   Proteomes; UP000011750; Chromosome A05.
DR   GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR   GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR   GO; GO:0047769; F:arogenate dehydratase activity; IBA:GO_Central.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IBA:GO_Central.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF00800; PDT; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Chloroplast {ECO:0000256|RuleBase:RU363004};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011750};
KW   Lyase {ECO:0000256|RuleBase:RU363004};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Plastid {ECO:0000256|RuleBase:RU363004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011750};
KW   Transit peptide {ECO:0000256|RuleBase:RU363004}.
FT   DOMAIN       98    273       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      287    373       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   REGION        1     35       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS      8     32       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   379 AA;  41508 MW;  BE502E3FCF328F50 CRC64;
     MAVHAVRSPT TQLPSGISGN LSPSNRNPNA VIRFGRGSSK RNRLASLSAS LREGDGRGKE
     SSVRAVEVKK ILEDSPLLPK PLSSNQLAET VSNGSRVRVA YQGVRGAYSE SAAEKAYPNC
     EAVPCEEFDT AFEAVERWLV DRAVLPIENS LGGSIHRNYD LLLRHNLHIV GEVKLAVRHC
     LLANHGVKLE DLRRVLSHPQ ALAQCENTLT RLGLVREAVD DTAGAAKQIA FEDLSDAAAV
     ASAKAAEIYG LNIVAEDIQD DTDNVTRFLM LAREPIIPGT NRLFKTSIVF SLEEGPGVLF
     KALAVFALRQ INLTKIESRP LRKNPLRASG GLKYFDYLFY VDFEASMADE VAQNALRHLE
     EFATFLRVLG SYPVDTTML
//
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