ID M4RF50_9BIFI Unreviewed; 722 AA.
AC M4RF50;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Aminoglycoside phosphotransferase {ECO:0000313|EMBL:AGH40804.1};
GN ORFNames=D805_0537 {ECO:0000313|EMBL:AGH40804.1};
OS Bifidobacterium thermophilum RBL67.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1254439 {ECO:0000313|EMBL:AGH40804.1, ECO:0000313|Proteomes:UP000011835};
RN [1] {ECO:0000313|EMBL:AGH40804.1, ECO:0000313|Proteomes:UP000011835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RBL67 {ECO:0000313|EMBL:AGH40804.1,
RC ECO:0000313|Proteomes:UP000011835};
RX PubMed=23640377;
RA Jans C., Lacroix C., Follador R., Stevens M.J.;
RT "Complete Genome Sequence of the Probiotic Bifidobacterium thermophilum
RT Strain RBL67.";
RL Genome Announc. 1:E00191-13(2013).
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DR EMBL; CP004346; AGH40804.1; -; Genomic_DNA.
DR AlphaFoldDB; M4RF50; -.
DR KEGG; btp:D805_0537; -.
DR PATRIC; fig|1254439.12.peg.540; -.
DR HOGENOM; CLU_023286_0_0_11; -.
DR Proteomes; UP000011835; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Transferase {ECO:0000313|EMBL:AGH40804.1}.
FT DOMAIN 108..256
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
FT REGION 309..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 614..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..441
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..637
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 76811 MW; D6FF0FADF0D2A3D8 CRC64;
MLAALASAVM PDISVAGVRA SNQGNATDEA RGIDHAVVQD SSGRLYDVHA SDTEAGRKHL
RGRIKAAQAL QRAKEPAALG FAVDRVLASS DGDDEHGPTG TTAVMVSPHF DGMSRPLDLL
TLDDCASVGT AIGAIHRLNP AFIPQEHYPA YATGQIRAQL VAWIKRLRQA GHIPQEITSS
WTAVLDTDGL WSFSTCLVHG GFHDGDILFS GSTITSIVNW QDMQINDPAR DLAWIFGKLD
EPHRNAVLAA YGRMLGSRLD SLIMLRANLW LQMEQVGEFI QALSDADSQK IIQFKAQVER
LAHQLSLATG SRSPAASIHR SDGKPPSTIT VGTLLDAGER RDAMLREEAR RKAAAQEADN
TNDALAQAGN AGNGEPSDQT NETDRTGSAQ IARATIKRDE TADSTKSSPV HAENAGNTRN
VGSSSEDTGD STASRPVTNP HSEAPTIAIK PPSFAIRGIQ VNNASGTIQT IDDDTRSETI
TVANAQGTQS VARNEIQGGT AHQTNDGGTN AARPEEGRGG QLAQPPARSA QSAQFQVQEA
TRHIGRNSNV ISETQSYVSA SVRVRKDGDA NVDGFADSDA ETVAFRAAEQ QSGDDEHAPE
TILIPLLERE ERAMRDARES LEAASRQQRH RDEASDVSNN PQDAGNQVSD GRSNAHANGD
GHSEPVISSG TDDSHGHAGQ ADKADQAERE QRDQQDRPAG QPTDANHGEE AAAGQSDTTP
KA
//
