ID M4S1X1_9SPHN Unreviewed; 548 AA.
AC M4S1X1;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=G432_03685 {ECO:0000313|EMBL:AGH48464.1};
OS Sphingomonas sp. MM-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=745310 {ECO:0000313|EMBL:AGH48464.1, ECO:0000313|Proteomes:UP000011816};
RN [1] {ECO:0000313|EMBL:AGH48464.1, ECO:0000313|Proteomes:UP000011816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM-1 {ECO:0000313|EMBL:AGH48464.1};
RX PubMed=23682148;
RA Tabata M., Ohtsubo Y., Ohhata S., Tsuda M., Nagata Y.;
RT "Complete Genome Sequence of the gamma-Hexachlorocyclohexane-Degrading
RT Bacterium Sphingomonas sp. Strain MM-1.";
RL Genome Announc. 1:E00247-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP004036; AGH48464.1; -; Genomic_DNA.
DR RefSeq; WP_015457479.1; NC_020561.1.
DR AlphaFoldDB; M4S1X1; -.
DR STRING; 745310.G432_03685; -.
DR KEGG; sphm:G432_03685; -.
DR PATRIC; fig|745310.14.peg.756; -.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_000445_114_39_5; -.
DR Proteomes; UP000011816; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AGH48464.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000011816};
KW Transferase {ECO:0000313|EMBL:AGH48464.1}.
FT DOMAIN 13..56
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 317..534
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 548 AA; 58958 MW; A866767A50885D8A CRC64;
MATVMTQKNE APPQPDLAAL LDLSHDTIFI RDGATGAISY WNAGAARVYG WEAADLAAPG
GYGRLQSRCD VPEETVLEEL ARTGHWQGGI TRTARDGSEI IVSARWAARL RPDGSIGEIV
ETARDVTVKA VAAEELRRSE YRYQNMFRAM AVSFWELDFS GVKGLLREWR DMGVEDFSAF
FAADPDAVRR VMGATRIVDV NEKTLLLFGA ADRAELGDTV ERFWPRDSEA VFAASVVAAI
SGKSNFEAET KMLTVDGREV EILFTCSFPP ECMGRGNVLV GVLDISGRVR AQEEVQRVQA
ELAHAARVAT LGELAASIAH EVNQPLAAIV NFGEAAKRWL NRPEPDMAEA AAAIERMIGD
SRRASDIIGR IRAMATKSVP KPTLFHPCEA VKEAVQLVRH DMQARGVALS IAEVEAVPRV
RADRIQIQQV AVNLIVNAVQ AMAQVPEDRR ALVIRTGLAG DNMVRIEVQD SGPGIDPVVA
DRLFTAFAST KDSGMGMGLS ISRSIVEAHG GTICGRGNEA APGATFSFTL PVAEMTADDA
AGACTAAA
//
