ID M4S275_9SPHN Unreviewed; 620 AA.
AC M4S275;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:AGH49003.1};
GN ORFNames=G432_06380 {ECO:0000313|EMBL:AGH49003.1};
OS Sphingomonas sp. MM-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=745310 {ECO:0000313|EMBL:AGH49003.1, ECO:0000313|Proteomes:UP000011816};
RN [1] {ECO:0000313|EMBL:AGH49003.1, ECO:0000313|Proteomes:UP000011816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM-1 {ECO:0000313|EMBL:AGH49003.1};
RX PubMed=23682148;
RA Tabata M., Ohtsubo Y., Ohhata S., Tsuda M., Nagata Y.;
RT "Complete Genome Sequence of the gamma-Hexachlorocyclohexane-Degrading
RT Bacterium Sphingomonas sp. Strain MM-1.";
RL Genome Announc. 1:E00247-13(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP004036; AGH49003.1; -; Genomic_DNA.
DR RefSeq; WP_015458016.1; NC_020561.1.
DR AlphaFoldDB; M4S275; -.
DR STRING; 745310.G432_06380; -.
DR KEGG; sphm:G432_06380; -.
DR PATRIC; fig|745310.14.peg.1323; -.
DR eggNOG; COG0840; Bacteria.
DR eggNOG; COG4564; Bacteria.
DR HOGENOM; CLU_000445_107_21_5; -.
DR Proteomes; UP000011816; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF17200; sCache_2; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011816};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 210..263
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 282..325
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 330..559
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT COILED 342..379
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 620 AA; 65030 MW; DF4C7D5477BAA7CC CRC64;
MHRLKIGGRL NLVSLAALTG LVVVLALSLL RLDTVMRDDI ADRTRKTVET AHSVLVHYQK
LESAGAMPRA DAQAAALAAI RAMRYGKDEY FWVNDMQPRM VMHPMNPALE GKDVGNNTDA
DGIYMFREMV KVVQAGGEGF VNYSWDKPGA NGAQPKISYV KGFAPWGWMI GSGVYVDEIR
AAVMKAAYVL GLAVLAVILA VGSLNWFLSR SISRPVVALT QRMRTLAEGD TGSAIPGLDR
RDEVGEMAAA LGVFRDAAVA KAAAEAEKAQ ADAEQQFVVT VVSDRLASLS DGDLTAAISE
EFPPAYAALK GNYNTAVGNL RDMMTALANS ADAIRTGSGE IAQASEDLAR RTEANAASLE
ETSAALSQME ERLRSTAAAA VHTAGQANEA IAIVGSGRAT ADEAVGAMGR VSESAQGIDS
VIEGLDKIAF QTRVLAMNAA VEAGRAGEAG RGFAVVADLV SALAMRSEEE AKRAREQLTA
TQSDIVMAVD AVQKVDGALA NISGSVEEVH KLVATMASDN QAQSATISEI TTAVGAMDQS
TQQNAAMVEE TSAAARNLAG EVEALSERSS RFRTGAAVAA RPRLAASASV AAPRPAPRPL
PMAQGSAAVD VFADQDWSSF
//
